HitPredict

Interactor 1: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Interactor 2: SYNCI (Q9H7C4)
Syncoilin (Syncoilin intermediate filament 1) (Syncoilin-1)
Gene: SYNC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 896 Hs			1 482
+	Hs
		280491 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		KT33A_HUMAN (125-478): 1.17e-106: 324: 17.30
+	Hs
		787892 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		KRT83_HUMAN (142-482): 8.4e-85: 271: 17.09
+	Hs
		213932 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		KRT86_HUMAN (142-482): 5.96e-83: 266: 17.09
+	Hs
		787940 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		K2C73_HUMAN (133-468): 3.32e-82: 265: 16.67
+	Hs
		787893 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		KRT85_HUMAN (142-482): 3.81e-81: 262: 16.81
+	Hs
		318787 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		K2C75_HUMAN (133-477): 2.66e-77: 253: 16.80
+	Hs
		787979 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		KRT82_HUMAN (142-481): 1.63e-76: 250: 17.42
+	Hs
		787928 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		K2C79_HUMAN (133-482): 7.52e-73: 241: 16.22
+	Hs
		531538 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		K2C5_HUMAN (133-473): 1.55e-63: 218: 16.71
+	Hs
		787912 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		K1H2_HUMAN (167-472): 5.79e-64: 215: 16.77
+	Hs
		787956 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		KRT35_HUMAN (167-470): 4.87e-63: 213: 17.50
+	Hs
		359470 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		K2C6A_HUMAN (133-481): 3.92e-61: 211: 17.44
+	Hs
		280780 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		KRT36_HUMAN (168-471): 2.92e-60: 206: 18.13
+	Hs
		280860 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		KRT37_HUMAN (167-476): 9.33e-57: 196: 17.49
+	Hs
		1078909 ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61		SYNCI_HUMAN (1-482): 9.08e-167: 481: 100.00
+	Hs
		535403 ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61		GFAP_HUMAN (154-456): 5.8e-99: 306: 23.27
+	Hs
		569085 ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61		DESM_HUMAN (154-456): 6.3e-86: 273: 20.76