HitPredict

Interactor 1: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Interactor 2: MYO6 (Q9UM54)
Unconventional myosin-VI (Unconventional myosin-6)
Gene: MYO6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26950368, 29467281
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005905 - clathrin-coated pit GO:0006897 - endocytosis and 1 others more... GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 896 Hs			1 1294
+	Hs
		1349284 ITSN2_HUMAN (3-845): 2.31e-61: 229: 14.40		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		1078932 ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		1353928 EP15R_HUMAN (417-891): 5.86e-14: 78.3: 11.98		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		724698 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Rn
		361106 MYH6_RAT (263-672): 2.44e-15: 83.3: 12.47		MYH6_RAT (759-1235): 5.4e-16: 86.3: 12.75
+	Hs
		522585 MYH7_HUMAN (256-608): 1.36e-14: 80.6: 11.14		MYH7_HUMAN (766-1261): 3.15e-15: 83.6: 11.01