Interactor 1: CASP2 (P42575)
Caspase-2 (CASP-2) (EC 3.4.22.55) (Neural precursor cell expressed developmentally down-regulated protein 2) (NEDD-2) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12]
Gene: CASP2
Interactor 2: CRADD (P78560)
Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain)
Gene: CRADD
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.985 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27107012, 8985253, 25416956, 15073321, 29875129, 32296183, 11156409, 23049853, unassigned1913, unassigned1304, 16652156, 31515488 |
| Identification Methods | two hybrid, pull down, affinity chromatography technology, validated two hybrid, anti tag coimmunoprecipitation, protein complementation assay, mammalian protein protein interaction trap, anti bait coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array and 3 others
more... |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CARD~CARD, CARD~Death |
| Common GO terms | GO:0005634 - nucleus GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006974 - DNA damage response and 6 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
