HitPredict

Interactor 1: FRK (P42685)
Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)
Gene: FRK

Interactor 2: SF3B4 (Q15427)
Splicing factor 3B subunit 4 (Pre-mRNA-splicing factor SF3b 49 kDa subunit) (Spliceosome-associated protein 49) (SAP 49)
Gene: SF3B4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	25416956, 21516116
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 424
+	Hs
		412206 FYN_HUMAN (30-503): 1.55e-177: 511: 50.63		SF3B4_HUMAN (1-424): 5.15e-61: 205: 100.00
+	Hs
		337482 ABL1_HUMAN (33-495): 1.24e-159: 484: 42.03		SF3B4_HUMAN (1-424): 5.15e-61: 205: 100.00
+	Hs
		522960 SRC_HUMAN (13-503): 1.23e-178: 513: 47.89		PABP4_HUMAN (4-188): 5.81e-40: 153: 38.17
+	Hs
		433366 YES_HUMAN (43-503): 6.27e-174: 502: 49.25		ELAV1_HUMAN (3-183): 2.25e-41: 151: 25.00
+	Hs
		516342 SRC_HUMAN (13-503): 1.23e-178: 513: 47.89		PABP1_HUMAN (90-181): 1.18e-11: 68.7: 27.17
+	Hs
		523147 SRC_HUMAN (13-503): 1.23e-178: 513: 47.89		PABP3_HUMAN (90-181): 8.71e-11: 65.7: 27.17
+	Ce
		371304 ABL1_CAEEL (45-495): 4.96e-167: 505: 43.89		SF3B4_CAEEL (88-364): 3.32e-10: 63.3: 14.79
+	Ce
		220214 SRC2_CAEEL (21-496): 5.79e-170: 490: 50.82		SF3B4_CAEEL (88-364): 3.32e-10: 63.3: 14.79
+	Ce
		106658 SRC1_CAEEL (43-501): 1.56e-156: 457: 47.03		SF3B4_CAEEL (88-364): 3.32e-10: 63.3: 14.79