HitPredict

Interactor 1: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 156 Hs			1 247
+	Hs
		790736 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		790755 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		909455 ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		910162 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		883468 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		905264 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		883467 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		982624 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		883491 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		683186 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		646707 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		926936 ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		646808 ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683816 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		927662 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		683234 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		883471 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		647383 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		646759 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		684398 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16