HitPredict

Interactor 1: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.516

Property	Details
Experiments	17955473
Identification Methods	pull down
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 449
+	Hs
		790811 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		428073 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		790743 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		965128 ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		428145 ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		883475 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		933351 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		933314 EHMT2_HUMAN (4-114): 3.84e-29: 113: 24.11		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		428113 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		428431 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		60278 POTEF_HUMAN (1-130): 1.26e-29: 115: 19.55		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		883476 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		883632 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		TBB2B_HUMAN (1-440): 0: 697: 40.23
+	Hs
		1313672 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		TBB2B_HUMAN (1-440): 0: 697: 40.23
+	Hs
		933974 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		60319 POTEF_HUMAN (1-130): 1.26e-29: 115: 19.55		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		60406 POTEF_HUMAN (1-130): 1.26e-29: 115: 19.55		TBB2B_HUMAN (1-440): 0: 697: 40.23
+	Hs
		1164344 POTEE_HUMAN (49-152): 2.11e-18: 82.7: 14.82		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		862023 DAPK1_HUMAN (49-155): 4.06e-14: 70.4: 22.02		TBB4B_HUMAN (1-437): 0: 697: 40.73