Protein: MURE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (EC 6.3.2.13) (Meso-A2pm-adding enzyme) (Meso-diaminopimelate-adding enzyme) (UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase) (UDP-MurNAc-tripeptide synthetase) (UDP-N-acetylmuramyl-tripeptide synthetase)

Gene: MURE
Organism: Escherichia coli K-12
Interactions: 25
UniProt ID: P22188

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0008360 - regulation of cell shape
GO:0008765 - UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

549482

MURF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase

1

5

High-throughput

0.618

High

604569

MURG
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

2

0

High-throughput

0.585

High

491553

KDSA
2-dehydro-3-deoxyphosphooctonate aldolase

2

0

High-throughput

0.576

High

491147

DNAK
Chaperone protein DnaK

1

3

High-throughput

0.536

High

616847

NADE
NH(3)-dependent NAD(+) synthetase

1

3

High-throughput

0.536

High

421123

PNP
Polyribonucleotide nucleotidyltransferase

1

0

High-throughput

0.513

High

489437

CARA
Carbamoyl phosphate synthase small chain

1

0

High-throughput

0.513

High

500092

CPXR
Transcriptional regulatory protein CpxR

1

0

High-throughput

0.513

High

559599

KATG
Catalase-peroxidase

1

0

High-throughput

0.513

High

578280

AMPP
Xaa-Pro aminopeptidase

1

0

High-throughput

0.513

High

493782

RS2
Small ribosomal subunit protein uS2

1

1

High-throughput

0.489

High

490520

EFG
Elongation factor G

1

1

High-throughput

0.479

High

497207

FTSE
Cell division ATP-binding protein FtsE

1

1

High-throughput

0.479

High

645664

HLDD
ADP-L-glycero-D-manno-heptose-6-epimerase

1

1

High-throughput

0.479

High

490371

COAD
Phosphopantetheine adenylyltransferase

1

0

High-throughput

0.464

High

493256

RS10
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

645666

YDAY
Protein YdaY

2

0

High-throughput

0.316

High

498910

KDTA
3-deoxy-D-manno-octulosonic acid transferase

2

0

High-throughput

0.307

High

645662

HYFB
Hydrogenase-4 component B

1

0

High-throughput

0.292

High

499297

GLCC
Glc operon transcriptional activator

1

0

High-throughput

0.282

High

645663

YHIJ
Uncharacterized protein YhiJ

1

0

High-throughput

0.282

High

645665

YAHN
Uncharacterized membrane protein YahN

1

0

High-throughput

0.282

High

645667

CBEA
Cytoskeleton bundling-enhancing antitoxin CbeA

1

0

High-throughput

0.282

High

500238

RSEP
Regulator of sigma-E protease RseP

1

0

High-throughput

0.253

Low

645668

YKGN
Putative transposase YkgN

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025