HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

The method score is based on:

Property	Details
Experiments	39079530, 32814053
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0005743 - mitochondrial inner membrane GO:0005759 - mitochondrial matrix and 6 others more... GO:0005829 - cytosol GO:0030672 - synaptic vesicle membrane GO:0043065 - positive regulation of apoptotic process GO:0043066 - negative regulation of apoptotic process GO:0043524 - negative regulation of neuron apoptotic process GO:0051402 - neuron apoptotic process
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	140
Hs

1	233

Service provided by Combinatics, Japan

Last updated: 11Aug2025