Interactor 1: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Interactor 2: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.749

The method score is based on:

Property Details
Experiments 25311206, 25959826, 15225551, 19487684, 25848931, 22854022, 23275563, 22119730
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, filter trap assay, x-ray fiber diffraction, transmission electron microscopy, classical fluorescence spectroscopy, anti tag coimmunoprecipitation, aggregation assay, two hybrid prey pooling approach, comigration in non denaturing gel electrophoresis and 1 others

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Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000132 - establishment of mitotic spindle orientation
GO:0002039 - p53 binding
GO:0005522 - profilin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 39 others

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Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 3142
Hs

1 3142
+ Mm

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Last updated: 15 Jul 2024