HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

The method score is based on:

Property	Details
Experiments	36634849, 34065515
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005938 - cell cortex GO:0008017 - microtubule binding and 4 others more... GO:0019904 - protein domain specific binding GO:0032991 - protein-containing complex GO:0043025 - neuronal cell body GO:0070840 - dynein complex binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	140
Hs

1	2115

Service provided by Combinatics, Japan

Last updated: 11Aug2025