HitPredict

Interactor 1: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Interactor 2: BRE1A (Q5VTR2)
E3 ubiquitin-protein ligase BRE1A (BRE1-A) (hBRE1) (EC 2.3.2.27) (RING finger protein 20) (RING-type E3 ubiquitin transferase BRE1A)
Gene: RNF20

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.664

The method score is based on:

Property Details
Experiments 23275563, 32814053, 17500595
Identification Methods two hybrid, two hybrid array, two hybrid pooling approach, validated two hybrid, two hybrid prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002039 - p53 binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 3142
Hs

1 975
+ Hs
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024