HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: PCLO (Q9Y6V0)
Protein piccolo (Aczonin)
Gene: PCLO

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	36634849, 39079530
Identification Methods	proximity labelling technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0008270 - zinc ion binding GO:0016079 - synaptic vesicle exocytosis GO:0030424 - axon
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 5142
+	Hs
		791617 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		SYTL4_HUMAN (4849-5130): 1.63e-38: 158: 18.27
+	Hs
		603191 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		KPCA_HUMAN (4696-4830): 1.82e-13: 79.3: 33.33
+	Rn
		790613 SYUA_RAT (1-140): 4.93e-58: 178: 95.00		KPCG_RAT (4696-4830): 1.19e-12: 76.6: 36.96
+	Hs
		791667 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		SYT3_HUMAN (4696-4827): 7.9e-13: 77: 36.03