Protein: SYTL4
Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin)

Gene: SYTL4
Organism: Homo sapiens
Interactions: 69
UniProt ID: Q96C24

Gene Ontology (top 5):
GO:0001778 - plasma membrane repair
GO:0005543 - phospholipid binding
GO:0005768 - endosome
GO:0005886 - plasma membrane
GO:0006886 - intracellular protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

902287

RB27A
Ras-related protein Rab-27A

10

20

Small-scale

0.975

High

955988

RAB8A
Ras-related protein Rab-8A

9

12

Small-scale

0.970

High

630433

RAB3A
Ras-related protein Rab-3A

6

20

Small-scale

0.943

High

126003

RB27B
Ras-related protein Rab-27B

4

20

Small-scale

0.906

High

1370773

RAB8B
Ras-related protein Rab-8B

2

12

High-throughput

0.811

High

1159617

STX1A
Syntaxin-1A

2

11

Small-scale

0.806

High

343187

RAB3D
Ras-related protein Rab-3D

2

20

High-throughput

0.783

High

374123

RASN
GTPase NRas

2

15

High-throughput

0.754

High

374837

RASH
GTPase HRas

2

12

High-throughput

0.754

High

375821

RASK
GTPase KRas

2

10

High-throughput

0.754

High

630605

RAB3B
Ras-related protein Rab-3B

2

20

Small-scale

0.754

High

976477

RB11A
Ras-related protein Rab-11A

2

3

Small-scale

0.754

High

1100706

STX3
Syntaxin-3

2

11

Small-scale

0.754

High

963453

STXB1
Syntaxin-binding protein 1

5

1

Small-scale

0.709

High

1385443

HM20A
High mobility group protein 20A

4

1

High-throughput

0.637

High

746214

STX2
Syntaxin-2

1

11

Small-scale

0.618

High

845751

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.618

High

900450

FXR2
RNA-binding protein FXR2

3

4

High-throughput

0.616

High

323519

TRI37
E3 ubiquitin-protein ligase TRIM37

2

3

High-throughput

0.606

High

725435

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

3

High-throughput

0.606

High

1357719

TRI41
E3 ubiquitin-protein ligase TRIM41

2

2

High-throughput

0.606

High

1371399

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

2

High-throughput

0.606

High

1385289

ZBTB9
Zinc finger and BTB domain-containing protein 9

2

5

High-throughput

0.606

High

1385449

LZTS1
Leucine zipper putative tumor suppressor 1

2

6

High-throughput

0.606

High

1385441

OSBL3
Oxysterol-binding protein-related protein 3

2

0

High-throughput

0.580

High

1385447

ZRAN1
Ubiquitin thioesterase ZRANB1

2

0

High-throughput

0.580

High

1340302

CEP70
Centrosomal protein of 70 kDa

2

1

High-throughput

0.573

High

180165

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

1

High-throughput

0.573

High

1259407

TBA1A
Tubulin alpha-1A chain

1

1

Small-scale

0.561

High

682084

RBTN1
Rhombotin-1

2

2

High-throughput

0.553

High

1287247

TBCD1
TBC1 domain family member 1

2

1

High-throughput

0.553

High

1385440

KIFC3
Kinesin-like protein KIFC3

2

1

High-throughput

0.553

High

1385451

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

2

High-throughput

0.536

High

1154557

CC85B
Coiled-coil domain-containing protein 85B

1

2

High-throughput

0.494

High

921387

MAP11
Methionine aminopeptidase 1

1

0

High-throughput

0.493

High

155689

FCHO1
F-BAR domain only protein 1

1

1

High-throughput

0.481

High

791617

SYUA
Alpha-synuclein

1

1

High-throughput

0.481

High

248998

EVI5
Ecotropic viral integration site 5 protein homolog

1

1

Small-scale

0.479

High

710420

EPHA2
Ephrin type-A receptor 2

1

1

High-throughput

0.479

High

787891

SRBP1
Sterol regulatory element-binding protein 1

1

1

High-throughput

0.479

High

827240

ARL1
ADP-ribosylation factor-like protein 1

1

3

High-throughput

0.479

High

862359

YAP1
Transcriptional coactivator YAP1

1

1

Small-scale

0.479

High

941826

ARL4C
ADP-ribosylation factor-like protein 4C

1

8

High-throughput

0.479

High

975172

ARF6
ADP-ribosylation factor 6

1

2

High-throughput

0.479

High

1326503

ARL14
ADP-ribosylation factor-like protein 14

1

7

High-throughput

0.479

High

1380898

ARL11
ADP-ribosylation factor-like protein 11

1

13

High-throughput

0.479

High

1385444

SAR1A
Small COPII coat GTPase SAR1A

1

7

High-throughput

0.479

High

1385445

ARL8B
ADP-ribosylation factor-like protein 8B

1

5

High-throughput

0.479

High

1385448

MYO5B
Unconventional myosin-Vb

1

3

Small-scale

0.479

High

1385450

TBC30
TBC1 domain family member 30

1

2

Small-scale

0.479

High

1385452

GIT1
ARF GTPase-activating protein GIT1

1

2

High-throughput

0.479

High

1385453

ARL5A
ADP-ribosylation factor-like protein 5A

1

4

High-throughput

0.479

High

1385454

SAR1B
Small COPII coat GTPase SAR1B

1

7

High-throughput

0.479

High

386068

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.470

High

2818

A0A0C3SFZ9
FCH and mu domain containing endocytic adaptor 1

1

1

High-throughput

0.470

High

346173

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

590930

TIMP2
Metalloproteinase inhibitor 2

1

0

High-throughput

0.458

High

1276614

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1071180

ARL16
ADP-ribosylation factor-like protein 16

1

5

High-throughput

0.437

High

1187524

AR13B
ADP-ribosylation factor-like protein 13B

1

10

High-throughput

0.437

High

1327119

FBXL6
F-box/LRR-repeat protein 6

1

3

High-throughput

0.437

High

1331234

ARL10
ADP-ribosylation factor-like protein 10

1

9

High-throughput

0.437

High

1385446

ARL15
ADP-ribosylation factor-like protein 15

1

4

High-throughput

0.437

High

1208319

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

2

0

High-throughput

0.316

High

1385442

ROP1A
Ropporin-1A

2

0

High-throughput

0.316

High

943402

H2BFS
Histone H2B type F-S

1

0

High-throughput

0.269

Low

1090487

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.269

Low

488532

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

0

Small-scale

0.249

Low

1385439

TMM79
Transmembrane protein 79

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025