HitPredict

Interactor 1: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Interactor 2: CNOT7 (Q9UIV1)
CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a)
Gene: CNOT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	25959826, 32814053
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 3142 Hs			1 285
+	Hs
		792050 HD_HUMAN (1-3142): 0: 5724: 100.00		CNOT8_HUMAN (1-282): 6.3e-172: 478: 76.24
+	Hs
		791867 HD_HUMAN (1-3142): 0: 5724: 100.00		Q96IQ6_HUMAN (1-285): 1.14e-150: 422: 85.97