Interactor 1: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Interactor 2: VPS28 (Q9UK41)
Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28)
Gene: VPS28

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.64 0.55 0.594

The method score is based on:

Property Details
Experiments 25959826, 32814053
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005769 - early endosome
GO:0005829 - cytosol
Homologous interactions 0

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Last updated: 15 Jul 2024