HitPredict

Interactor 1: LIS1 (P43034)
Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
Gene: PAFAH1B1

Interactor 2: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29955894
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 410 Hs			1 835
+	Hs
		903194 WDR5_HUMAN (4-323): 1.79e-70: 226: 25.38		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		1029841 TBL1R_HUMAN (22-265): 2.5e-57: 197: 20.08		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		921549 GBB2_HUMAN (166-410): 8.15e-51: 175: 20.48		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		1029940 NLE1_HUMAN (1-219): 4.29e-44: 161: 22.51		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		929437 RACK1_HUMAN (103-261): 2.66e-16: 80.9: 33.13		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		197013 PRP4_HUMAN (324-409): 2.67e-13: 73.3: 15.96		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		668564 WDR5_HUMAN (4-323): 1.79e-70: 226: 25.38		PML_HUMAN (29-609): 1.21e-57: 214: 14.00
+	Mm
		903669 WDR5_MOUSE (4-323): 1.79e-70: 226: 25.38		KMT2C_MOUSE (63-719): 5.81e-52: 200: 11.22
+	Hs
		668886 FBXW7_HUMAN (261-409): 5.02e-27: 115: 30.00		PML_HUMAN (29-609): 1.21e-57: 214: 14.00
+	Hs
		175666 RACK1_HUMAN (103-261): 2.66e-16: 80.9: 33.13		TRI18_HUMAN (56-644): 5.73e-67: 237: 13.78
+	Hs
		1281351 FBXW7_HUMAN (261-409): 5.02e-27: 115: 30.00		TRI56_HUMAN (47-532): 1.21e-51: 195: 17.68
+	Hs
		929662 RACK1_HUMAN (103-261): 2.66e-16: 80.9: 33.13		TRI45_HUMAN (64-544): 3.21e-62: 222: 16.70
+	Hs
		668898 SNR40_HUMAN (328-408): 1.73e-17: 85.2: 26.83		PML_HUMAN (29-609): 1.21e-57: 214: 14.00
+	Hs
		585027 FBXW7_HUMAN (261-409): 5.02e-27: 115: 30.00		RO52_HUMAN (104-502): 1.58e-48: 180: 12.94
+	Hs
		196959 PRP4_HUMAN (324-409): 2.67e-13: 73.3: 15.96		PML_HUMAN (29-609): 1.21e-57: 214: 14.00
+	Hs
		929725 RACK1_HUMAN (103-261): 2.66e-16: 80.9: 33.13		TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32
+	Hs
		734586 RACK1_HUMAN (103-261): 2.66e-16: 80.9: 33.13		TRI23_HUMAN (38-421): 2.37e-56: 205: 14.42
+	Hs
		170444 SNR40_HUMAN (328-408): 1.73e-17: 85.2: 26.83		TIF1A_HUMAN (404-808): 1.31e-52: 200: 21.55