HitPredict

Interactor 1: PE2R3 (P43115)
Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor)
Gene: PTGER3

Interactor 2: TNPO3 (Q9Y5L0)
Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR)
Gene: TNPO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 390 Hs			1 923
+	Hs
		723121 OPRM_HUMAN (3-389): 2.49e-61: 204: 17.13		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		162445 APJ_HUMAN (37-390): 1.01e-63: 210: 14.41		XPO1_HUMAN (3-920): 6.76e-151: 475: 12.37
+	Hs
		297159 OPRM_HUMAN (3-389): 2.49e-61: 204: 17.13		IPO13_HUMAN (5-923): 2.1e-143: 452: 21.02
+	Hs
		312201 PE2R3_HUMAN (1-390): 1.16e-69: 226: 100.00		IPO7_HUMAN (13-813): 8.63e-101: 340: 11.63
+	Hs
		155546 PE2R3_HUMAN (1-390): 1.16e-69: 226: 100.00		TNPO2_HUMAN (68-784): 3.33e-92: 313: 12.26
+	Hs
		178126 PE2R3_HUMAN (1-390): 1.16e-69: 226: 100.00		IPO8_HUMAN (10-813): 5.2e-89: 307: 9.92
+	Hs
		178120 APJ_HUMAN (37-390): 1.01e-63: 210: 14.41		IPO8_HUMAN (10-813): 5.2e-89: 307: 9.92
+	Hs
		155531 EDNRB_HUMAN (5-388): 2.31e-59: 200: 13.85		TNPO2_HUMAN (68-784): 3.33e-92: 313: 12.26
+	Hs
		723407 APJ_HUMAN (37-390): 1.01e-63: 210: 14.41		XPO5_HUMAN (9-614): 3.04e-22: 105: 14.21
+	Hs
		623000 EDNRB_HUMAN (5-388): 2.31e-59: 200: 13.85		Q4LE60_HUMAN (161-691): 3.09e-11: 69.5: 9.70