HitPredict

Interactor 1: MUC18 (P43121)
Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146)
Gene: MCAM

Interactor 2: MINK1 (Q8N4C8)
Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)
Gene: MINK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	38117590
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~V-set
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 1332
+	Hs
		793516 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		TNIK_HUMAN (1-1332): 0: 1098: 60.83
+	Hs
		324758 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Mm
		1206831 PTK7_MOUSE (141-613): 9.65e-54: 201: 15.07		MINK1_MOUSE (1-1332): 0: 1235: 93.46
+	Mm
		956967 PTK7_MOUSE (141-613): 9.65e-54: 201: 15.07		M4K4_MOUSE (1-1332): 0: 993: 56.32
+	Hs
		234459 DSCAM_HUMAN (265-506): 2.21e-09: 63.2: 25.76		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		793364 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		MARK2_HUMAN (8-747): 3.42e-132: 427: 14.86
+	Hs
		793541 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		M4K5_HUMAN (5-307): 6.97e-71: 257: 45.60
+	Dm
		1249844 Q9VQW7_DROME (25-345): 8.83e-21: 99.6: 16.42		HIPPO_DROME (16-374): 2.99e-115: 377: 37.09
+	Hs
		234524 DSCAM_HUMAN (265-506): 2.21e-09: 63.2: 25.76		M3K11_HUMAN (26-779): 1.45e-120: 397: 21.38