HitPredict

Interactor 1: MUC18 (P43121)
Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146)
Gene: MCAM

Interactor 2: NPTN (Q9Y639)
Neuroplastin (Stromal cell-derived receptor 1) (SDR-1)
Gene: NPTN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	38117590
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C2-set_2~Ig_3, Ig_3~Ig_3, Ig_3~V-set
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 398
+	Hs
		726073 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		BASI_HUMAN (10-398): 5.47e-66: 216: 38.33
+	Hs
		793290 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		CNTN1_HUMAN (29-334): 1.17e-33: 135: 18.65
+	Ce
		103933 SAX3_CAEEL (6-637): 7.59e-95: 319: 14.96		SAX3_CAEEL (2-398): 5.39e-56: 200: 17.81
+	Hs
		793551 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		ROBO1_HUMAN (225-379): 6.67e-22: 100: 20.25
+	Hs
		1336275 ROBO2_HUMAN (1-646): 1.16e-96: 325: 14.69		ROBO1_HUMAN (225-379): 6.67e-22: 100: 20.25
+	Hs
		1336269 ROBO2_HUMAN (1-646): 1.16e-96: 325: 14.69		ROBO2_HUMAN (2-384): 2.18e-21: 98.5: 11.72
+	Mm
		1206820 PTK7_MOUSE (141-613): 9.65e-54: 201: 15.07		PTK7_MOUSE (33-346): 8.61e-37: 144: 18.29
+	Mm
		1149039 CNTN4_MOUSE (20-612): 2.95e-44: 172: 15.30		CNTN4_MOUSE (8-398): 3.71e-45: 169: 16.34
+	Mm
		1142535 CNTN2_MOUSE (17-604): 4.83e-56: 207: 11.82		CNTN2_MOUSE (29-331): 7.24e-33: 132: 20.71
+	Hs
		1018289 CNTN1_HUMAN (19-642): 1.11e-44: 173: 13.26		CNTN1_HUMAN (29-334): 1.17e-33: 135: 18.65
+	Hs
		970115 CNTN2_HUMAN (266-635): 1.01e-44: 173: 13.04		CNTN1_HUMAN (29-334): 1.17e-33: 135: 18.65
+	Mm
		1186724 PTK7_MOUSE (141-613): 9.65e-54: 201: 15.07		Q7TQG5_MOUSE (30-388): 9.04e-15: 78.5: 12.92
+	Dm
		1372240 Q9VQ08_DROME (378-643): 1.42e-22: 105: 13.72		Q9VQ08_DROME (3-397): 4.71e-45: 168: 15.00
+	Mm
		530206 CNTN2_MOUSE (17-604): 4.83e-56: 207: 11.82		NCAM1_MOUSE (2-185): 2.18e-10: 64.6: 13.04
+	Mm
		530211 PTK7_MOUSE (141-613): 9.65e-54: 201: 15.07		NCAM1_MOUSE (2-185): 2.18e-10: 64.6: 13.04
+	Mm
		530200 NCAM1_MOUSE (255-646): 5.9e-53: 198: 14.98		NCAM1_MOUSE (2-185): 2.18e-10: 64.6: 13.04
+	Dm
		219801 O44924_DROME (337-636): 3.76e-37: 151: 12.35		O44924_DROME (3-232): 3.2e-16: 82.7: 13.28