Interactor 1: GLP1R (P43220)
Glucagon-like peptide 1 receptor (GLP-1 receptor) (GLP-1-R) (GLP-1R)
Gene: GLP1R

Interactor 2: GNAS2 (P63092)
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Adenylate cyclase-stimulating G alpha protein)
Gene: GNAS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 26272612
Identification Methods protein complementation assay
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_2~G-alpha
Common GO terms GO:0005886 - plasma membrane
GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 - activation of adenylate cyclase activity
GO:0016020 - membrane
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 463
Hs

1 394
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024