HitPredict

Interactor 1: MATR3 (P43243)
Matrin-3
Gene: MATR3

Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29511296, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0016020 - membrane GO:0035198 - miRNA binding GO:0045087 - innate immune response
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 847 Hs			1 783
+	Hs
		794059 MATR3_HUMAN (1-847): 0: 1198: 100.00		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		133917 MATR3_HUMAN (1-847): 0: 1198: 100.00		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571343 MATR3_HUMAN (1-847): 0: 1198: 100.00		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		757497 MATR3_HUMAN (1-847): 0: 1198: 100.00		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		541170 HNRPL_HUMAN (386-644): 2.18e-74: 256: 16.09		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		541086 HNRPL_HUMAN (386-644): 2.18e-74: 256: 16.09		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		540891 HNRPL_HUMAN (386-644): 2.18e-74: 256: 16.09		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		1060607 ZN638_HUMAN (650-843): 4.53e-20: 98.4: 22.97		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		321002 PTBP3_HUMAN (333-622): 5.16e-90: 297: 15.39		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		540915 HNRPL_HUMAN (386-644): 2.18e-74: 256: 16.09		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		757647 RBM20_HUMAN (587-846): 3.96e-23: 107: 20.15		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23