HitPredict

Interactor 1: MATR3 (P43243)
Matrin-3
Gene: MATR3

Interactor 2: PTBP2 (Q9UKA9)
Polypyrimidine tract-binding protein 2 (Neural polypyrimidine tract-binding protein) (Neurally-enriched homolog of PTB) (PTB-like protein)
Gene: PTBP2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.690

Property	Details
Experiments	32296183, 22365833, 21516116, unassigned1304
Identification Methods	two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 847 Hs			1 531
+	Hs
		643443 MATR3_HUMAN (1-847): 0: 1198: 100.00		PTBP1_HUMAN (1-531): 3.71e-124: 376: 66.43
+	Hs
		321006 MATR3_HUMAN (1-847): 0: 1198: 100.00		PTBP3_HUMAN (1-531): 3.32e-114: 350: 65.10
+	Hs
		540922 MATR3_HUMAN (1-847): 0: 1198: 100.00		HNRPL_HUMAN (47-529): 6.83e-62: 215: 23.00
+	Hs
		793940 MATR3_HUMAN (1-847): 0: 1198: 100.00		PABP4_HUMAN (47-280): 1.83e-30: 127: 12.03
+	Hs
		793928 MATR3_HUMAN (1-847): 0: 1198: 100.00		ELAV2_HUMAN (327-530): 9.38e-25: 107: 15.81
+	Hs
		643426 PTBP1_HUMAN (329-604): 1.42e-92: 304: 17.86		PTBP1_HUMAN (1-531): 3.71e-124: 376: 66.43
+	Hs
		643620 PTBP1_HUMAN (329-604): 1.42e-92: 304: 17.86		PTBP2_HUMAN (1-531): 2.3e-121: 368: 100.00
+	Hs
		321242 PTBP3_HUMAN (333-622): 5.16e-90: 297: 15.39		PTBP2_HUMAN (1-531): 2.3e-121: 368: 100.00
+	Hs
		320980 PTBP1_HUMAN (329-604): 1.42e-92: 304: 17.86		PTBP3_HUMAN (1-531): 3.32e-114: 350: 65.10
+	Hs
		1356358 PTBP2_HUMAN (329-625): 1.45e-85: 284: 15.50		PTBP2_HUMAN (1-531): 2.3e-121: 368: 100.00
+	Hs
		643554 PTBP1_HUMAN (329-604): 1.42e-92: 304: 17.86		HNRLL_HUMAN (41-530): 1.2e-67: 229: 24.95
+	Hs
		540901 PTBP1_HUMAN (329-604): 1.42e-92: 304: 17.86		HNRPL_HUMAN (47-529): 6.83e-62: 215: 23.00
+	Dm
		1181642 Q7KRS7_DROME (333-627): 1.62e-78: 268: 14.65		Q8IHH3_DROME (275-529): 2.9e-73: 240: 22.39
+	Dm
		56217 Q95UI6_DROME (338-627): 8.93e-75: 262: 14.57		A1ZBN3_DROME (272-529): 2e-74: 243: 22.51
+	Hs
		321063 PTBP3_HUMAN (333-622): 5.16e-90: 297: 15.39		ELAV2_HUMAN (327-530): 9.38e-25: 107: 15.81
+	Hs
		311330 PTBP3_HUMAN (333-622): 5.16e-90: 297: 15.39		CELF2_HUMAN (109-262): 1.23e-11: 68.9: 16.46
+	Dm
		90924 Q95UI6_DROME (338-627): 8.93e-75: 262: 14.57		E1JJ45_DROME (3-258): 8.44e-17: 85.1: 17.05