HitPredict

Interactor 1: GRK6 (P43250)
G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6)
Gene: GRK6

Interactor 2: SYUB (Q16143)
Beta-synuclein
Gene: SNCB

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10852916
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 576 Hs			1 134
+	Hs
		742110 GRK6_HUMAN (1-576): 0: 573: 100.00		SYUA_HUMAN (1-134): 1.75e-43: 141: 60.69
+	Hs
		282772 GRK6_HUMAN (1-576): 0: 573: 100.00		SYUG_HUMAN (1-102): 2.2e-24: 92.2: 59.29
+	Hs
		714539 GRK5_HUMAN (1-563): 1.85e-175: 510: 71.76		SYUB_HUMAN (1-127): 7.32e-46: 147: 100.00
+	Hs
		714489 GRK5_HUMAN (1-563): 1.85e-175: 510: 71.76		SYUA_HUMAN (1-134): 1.75e-43: 141: 60.69
+	Hs
		282769 GRK5_HUMAN (1-563): 1.85e-175: 510: 71.76		SYUG_HUMAN (1-102): 2.2e-24: 92.2: 59.29
+	Hs
		1079321 GRK1_HUMAN (3-537): 1.99e-153: 453: 47.96		SYUB_HUMAN (1-127): 7.32e-46: 147: 100.00
+	Hs
		742316 GRK1_HUMAN (3-537): 1.99e-153: 453: 47.96		SYUA_HUMAN (1-134): 1.75e-43: 141: 60.69
+	Hs
		742230 KPCE_HUMAN (11-507): 2.06e-147: 444: 24.09		SYUA_HUMAN (1-134): 1.75e-43: 141: 60.69
+	Hs
		626629 ARBK1_HUMAN (2-541): 2.79e-147: 442: 36.59		SYUA_HUMAN (1-134): 1.75e-43: 141: 60.69
+	Rn
		448412 KPCE_RAT (11-507): 1.72e-145: 439: 24.28		SYUA_RAT (1-134): 6.13e-44: 142: 60.69
+	Hs
		742241 KPCD_HUMAN (9-518): 2.81e-144: 434: 24.86		SYUA_HUMAN (1-134): 1.75e-43: 141: 60.69
+	Hs
		681868 AKT1_HUMAN (75-497): 3.54e-143: 424: 30.59		SYUB_HUMAN (1-127): 7.32e-46: 147: 100.00
+	Hs
		681700 AKT1_HUMAN (75-497): 3.54e-143: 424: 30.59		SYUA_HUMAN (1-134): 1.75e-43: 141: 60.69
+	Hs
		282779 GRK1_HUMAN (3-537): 1.99e-153: 453: 47.96		SYUG_HUMAN (1-102): 2.2e-24: 92.2: 59.29
+	Hs
		566312 KPCA_HUMAN (176-496): 1.87e-58: 208: 38.08		SYUA_HUMAN (1-134): 1.75e-43: 141: 60.69