HitPredict

Interactor 1: H14 (P43274)
Histone H1.4 (H1 VAR.2) (H1e)
Gene: H1-4

Interactor 2: EED (Q921E6)
Polycomb protein EED
Gene: EED

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 219 Mm			1 441
+	Hs
		267878 H12_HUMAN (1-178): 1.26e-20: 87.6: 87.71		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		268034 H11_HUMAN (38-148): 7.33e-15: 72.2: 72.97		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		550505 H12_MOUSE (1-115): 3.47e-14: 70.6: 88.70		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		489187 H14_HUMAN (1-115): 3.11e-20: 86.8: 97.39		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		559202 H15_HUMAN (1-157): 1.7e-15: 74.1: 80.63		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		559886 H12_HUMAN (1-178): 1.26e-20: 87.6: 87.71		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		489195 H14_HUMAN (1-115): 3.11e-20: 86.8: 97.39		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		608517 H1T_HUMAN (1-197): 1.72e-25: 100: 51.94		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		559595 H12_HUMAN (1-178): 1.26e-20: 87.6: 87.71		LIS1_HUMAN (332-438): 2.37e-14: 76.5: 18.69
+	Hs
		559632 H12_HUMAN (1-178): 1.26e-20: 87.6: 87.71		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		488971 H14_HUMAN (1-115): 3.11e-20: 86.8: 97.39		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		903144 H11_HUMAN (38-148): 7.33e-15: 72.2: 72.97		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09