HitPredict

Interactor 1: H11 (P43275)
Histone H1.1 (H1 VAR.3) (Histone H1a) (H1a)
Gene: H1-1

Interactor 2: CDK2 (P97377)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2)
Gene: CDK2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.744

Property	Details
Experiments	15707957, 8547220, 8226784, 15749021, 17371838, 12007403, 14627988
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 213 Mm			1 346
+	Rn
		413197 H1T_RAT (1-201): 3.81e-36: 127: 49.25		Q6P751_RAT (1-346): 1.09e-141: 404: 83.82
+	Mm
		794656 H15_MOUSE (1-196): 9.52e-22: 90.9: 60.29		CDK2_MOUSE (1-346): 6.83e-152: 432: 100.00
+	Mm
		550489 H12_MOUSE (32-117): 4.78e-17: 78.2: 80.23		CDK2_MOUSE (1-346): 6.83e-152: 432: 100.00
+	Rn
		88903 H11_RAT (1-124): 5.9e-25: 99: 92.74		Q6P751_RAT (1-346): 1.09e-141: 404: 83.82
+	Hs
		559328 H13_HUMAN (1-162): 1.31e-23: 95.5: 59.28		CDK2_HUMAN (1-346): 6.94e-142: 405: 82.95
+	Hs
		558990 H15_HUMAN (1-117): 1.41e-20: 87.8: 68.64		CDK2_HUMAN (1-346): 6.94e-142: 405: 82.95
+	Hs
		625377 H11_HUMAN (40-145): 6.4e-17: 77.8: 76.15		CDK2_HUMAN (1-346): 6.94e-142: 405: 82.95
+	Rn
		88899 H11_RAT (1-124): 5.9e-25: 99: 92.74		CDK1_RAT (1-337): 1.22e-126: 366: 55.62
+	Hs
		414717 H13_HUMAN (1-162): 1.31e-23: 95.5: 59.28		CDK1_HUMAN (1-337): 1.36e-126: 366: 56.21
+	Hs
		414716 H15_HUMAN (1-117): 1.41e-20: 87.8: 68.64		CDK1_HUMAN (1-337): 1.36e-126: 366: 56.21
+	Hs
		559352 H13_HUMAN (1-162): 1.31e-23: 95.5: 59.28		CDK7_HUMAN (2-346): 1.01e-122: 358: 38.22
+	Mm
		509472 H11_MOUSE (1-181): 1.43e-19: 84.7: 100.00		CDK1_MOUSE (1-337): 8.33e-126: 364: 55.62
+	Hs
		488949 H14_HUMAN (1-117): 1.45e-21: 90.1: 73.50		CDK7_HUMAN (2-346): 1.01e-122: 358: 38.22
+	Hs
		559612 H12_HUMAN (1-180): 1.1e-20: 87.8: 57.78		CDK7_HUMAN (2-346): 1.01e-122: 358: 38.22
+	Hs
		489003 H14_HUMAN (1-117): 1.45e-21: 90.1: 73.50		CDK5_HUMAN (1-340): 1.64e-122: 355: 46.04
+	Hs
		414874 H11_HUMAN (40-145): 6.4e-17: 77.8: 76.15		CDK1_HUMAN (1-337): 1.36e-126: 366: 56.21
+	Hs
		559065 H15_HUMAN (1-117): 1.41e-20: 87.8: 68.64		CDK5_HUMAN (1-340): 1.64e-122: 355: 46.04
+	Hs
		559654 H12_HUMAN (1-180): 1.1e-20: 87.8: 57.78		CDK5_HUMAN (1-340): 1.64e-122: 355: 46.04
+	Mm
		509461 H12_MOUSE (32-117): 4.78e-17: 78.2: 80.23		CDK1_MOUSE (1-337): 8.33e-126: 364: 55.62
+	Mm
		794639 H11_MOUSE (1-181): 1.43e-19: 84.7: 100.00		CDK5_MOUSE (1-340): 2.22e-122: 355: 46.33