Protein: U2AFM
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (Renal carcinoma antigen NY-REN-20) (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (U2AF35-related protein) (URP)

Gene: U2AFM, ZRSR2
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q15696

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex
GO:0005689 - U12-type spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

942684

SRPK2
SRSF protein kinase 2

8

8

High-throughput

0.975

High

1077219

SRPK1
SRSF protein kinase 1

4

7

High-throughput

0.910

High

833886

CLK2
Dual specificity protein kinase CLK2

4

4

High-throughput

0.904

High

165491

SR140
U2 snRNP-associated SURP motif-containing protein

3

1

High-throughput

0.861

High

856077

RBM5
RNA-binding protein 5

3

2

High-throughput

0.861

High

1034298

SF3B2
Splicing factor 3B subunit 2

3

1

High-throughput

0.861

High

1077199

U1SBP
U11/U12 small nuclear ribonucleoprotein 35 kDa protein

3

7

High-throughput

0.861

High

1077212

ZCRB1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1

3

5

High-throughput

0.861

High

1077216

SPF45
Splicing factor 45

3

11

High-throughput

0.861

High

1077217

RNPC3
RNA-binding region-containing protein 3

3

3

High-throughput

0.861

High

268736

SF3B1
Splicing factor 3B subunit 1

4

0

High-throughput

0.857

High

1077193

U2AFL
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1

3

10

High-throughput

0.818

High

1018806

SF3A3
Splicing factor 3A subunit 3

3

0

High-throughput

0.816

High

1077226

ZMAT5
Zinc finger matrin-type protein 5

3

0

High-throughput

0.816

High

1028668

SRSF5
Serine/arginine-rich splicing factor 5

2

6

High-throughput

0.783

High

1077198

U2AFM
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2

2

10

High-throughput

0.783

High

673798

NKTR
NK-tumor recognition protein

3

1

High-throughput

0.770

High

596759

CD11B
Cyclin-dependent kinase 11B

2

2

High-throughput

0.705

High

1077222

SDCB2
Syntenin-2

4

1

High-throughput

0.698

High

1077232

SF3B6
Splicing factor 3B subunit 6

1

6

High-throughput

0.691

High

911849

RUXF
Small nuclear ribonucleoprotein F

3

1

High-throughput

0.675

High

990074

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

3

1

High-throughput

0.667

High

1074124

SF3A1
Splicing factor 3A subunit 1

3

3

High-throughput

0.667

High

1077203

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

3

2

High-throughput

0.667

High

1077209

CHERP
Calcium homeostasis endoplasmic reticulum protein

3

4

High-throughput

0.667

High

1072997

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.656

High

64859

SRRM4
Serine/arginine repetitive matrix protein 4

3

2

High-throughput

0.654

High

1077202

SNR48
U11/U12 small nuclear ribonucleoprotein 48 kDa protein

3

0

High-throughput

0.638

High

1077210

PDCD7
Programmed cell death protein 7

3

0

High-throughput

0.638

High

1077220

NADAP
Kanadaptin

3

0

High-throughput

0.638

High

538975

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

2

High-throughput

0.628

High

927960

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

5

High-throughput

0.628

High

992788

SRSF1
Serine/arginine-rich splicing factor 1

1

6

High-throughput

0.621

High

1077228

FZR1
Fizzy-related protein homolog

1

5

High-throughput

0.618

High

912051

RUXG
Small nuclear ribonucleoprotein G

2

5

High-throughput

0.611

High

1077200

SPT2
Protein SPT2 homolog

2

4

High-throughput

0.611

High

1077204

TTC33
Tetratricopeptide repeat protein 33

3

1

High-throughput

0.609

High

1077224

TRPM3
Transient receptor potential cation channel subfamily M member 3

3

1

High-throughput

0.609

High

911656

RUXE
Small nuclear ribonucleoprotein E

2

0

High-throughput

0.602

High

1077231

LC7L2
Putative RNA-binding protein Luc7-like 2

3

1

High-throughput

0.597

High

1077207

KHDC4
KH homology domain-containing protein 4

2

0

High-throughput

0.580

High

1023047

STK4
Serine/threonine-protein kinase 4

1

4

High-throughput

0.575

High

833741

CLK1
Dual specificity protein kinase CLK1

1

4

High-throughput

0.555

High

1077201

REP15
Rab15 effector protein

2

1

High-throughput

0.553

High

1077214

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

1

High-throughput

0.553

High

912644

SMD3
Small nuclear ribonucleoprotein Sm D3

1

3

High-throughput

0.536

High

806022

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

912468

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.513

High

1077206

PHF5A
PHD finger-like domain-containing protein 5A

1

0

High-throughput

0.513

High

386801

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

300159

PRP6
Pre-mRNA-processing factor 6

1

0

High-throughput

0.460

High

1077205

RS27L
Ribosomal protein eS27-like

1

0

High-throughput

0.460

High

1077225

SPS2L
SPATS2-like protein

1

0

High-throughput

0.460

High

199754

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

0

High-throughput

0.458

High

1077221

GTPB4
GTP-binding protein 4

1

0

High-throughput

0.458

High

68424

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

5

High-throughput

0.445

High

1077208

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.438

High

1077230

ADIP
Afadin- and alpha-actinin-binding protein

4

0

High-throughput

0.368

High

787731

HUTH
Histidine ammonia-lyase

3

0

High-throughput

0.347

High

839482

SPB8
Serpin B8

3

0

High-throughput

0.347

High

1077211

GPT11
G patch domain-containing protein 11

3

0

High-throughput

0.347

High

1077215

CCD97
Coiled-coil domain-containing protein 97

3

0

High-throughput

0.347

High

1077229

RL26L
Ribosomal protein uL24-like

3

0

High-throughput

0.342

High

1077213

TP8L1
Tumor necrosis factor alpha-induced protein 8-like protein 1

2

0

High-throughput

0.316

High

1077218

AP4AT
AP-4 complex accessory subunit Tepsin

2

0

High-throughput

0.316

High

1077227

CCNL1
Cyclin-L1

2

0

High-throughput

0.316

High

1062528

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.279

Low

394765

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

899213

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.249

Low

922574

RL10A
Large ribosomal subunit protein uL1

1

0

High-throughput

0.249

Low

1077223

CH033
UPF0488 protein C8orf33

1

0

High-throughput

0.249

Low

886284

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024