HitPredict

Interactor 1: UBP6 (P43593)
Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.4.19.12) (Deubiquitinating enzyme 6) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6)
Gene: UBP6

Interactor 2: RPN14 (P53196)
26S proteasome regulatory subunit RPN14 (Proteasome non-ATPase subunit 14)
Gene: RPN14

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	37968396, 19446323
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	UCH~WD40
Common GO terms	GO:0000502 - proteasome complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 499 Sc			1 417
+	Hs
		870889 UBP14_HUMAN (5-499): 1.27e-103: 320: 29.12		PAAF1_HUMAN (90-353): 2.5e-62: 207: 26.30
+	Hs
		863385 UBP14_HUMAN (5-499): 1.27e-103: 320: 29.12		COPA_HUMAN (129-415): 2.05e-52: 190: 11.15
+	Hs
		903571 UBP36_HUMAN (3-496): 3.71e-76: 261: 14.46		WDR5_HUMAN (217-415): 1.93e-39: 145: 11.50
+	Hs
		903231 UBP10_HUMAN (2-499): 2.81e-76: 257: 14.18		WDR5_HUMAN (217-415): 1.93e-39: 145: 11.50
+	Hs
		209481 UBP42_HUMAN (22-496): 2.32e-75: 260: 15.28		PLRG1_HUMAN (41-271): 3.95e-35: 137: 18.46
+	Hs
		870866 UBP14_HUMAN (5-499): 1.27e-103: 320: 29.12		SNR40_HUMAN (2-120): 3.37e-14: 75.1: 8.66
+	Hs
		1346960 UBP36_HUMAN (3-496): 3.71e-76: 261: 14.46		NLE1_HUMAN (325-416): 1.08e-14: 77.4: 13.98
+	Hs
		1288358 UBP36_HUMAN (3-496): 3.71e-76: 261: 14.46		SNR40_HUMAN (2-120): 3.37e-14: 75.1: 8.66
+	Hs
		1288312 UBP42_HUMAN (22-496): 2.32e-75: 260: 15.28		SNR40_HUMAN (2-120): 3.37e-14: 75.1: 8.66
+	Hs
		271161 UBP2_HUMAN (79-495): 6.9e-82: 267: 15.79		FBXW7_HUMAN (316-416): 1.38e-10: 65.1: 14.71
+	Hs
		1058218 UBP10_HUMAN (2-499): 2.81e-76: 257: 14.18		SMU1_HUMAN (60-205): 2.82e-13: 73.3: 20.51
+	Hs
		1281441 UBP36_HUMAN (3-496): 3.71e-76: 261: 14.46		FBXW7_HUMAN (316-416): 1.38e-10: 65.1: 14.71
+	Hs
		1058268 UBP10_HUMAN (2-499): 2.81e-76: 257: 14.18		FBXW7_HUMAN (316-416): 1.38e-10: 65.1: 14.71
+	Dm
		1362568 PUF_DROME (3-497): 8.21e-73: 253: 16.45		FBXW7_DROME (316-414): 1.2e-11: 68.9: 14.00
+	Hs
		849963 UBP11_HUMAN (325-499): 1.73e-30: 127: 18.64		COPA_HUMAN (129-415): 2.05e-52: 190: 11.15
+	Hs
		1273692 USP9X_HUMAN (87-497): 2.59e-65: 231: 16.63		FBXW7_HUMAN (316-416): 1.38e-10: 65.1: 14.71
+	Hs
		903417 UBP7_HUMAN (100-347): 5.03e-30: 126: 21.26		WDR5_HUMAN (217-415): 1.93e-39: 145: 11.50
+	Hs
		1281331 UBP28_HUMAN (273-494): 8.5e-14: 76.1: 18.29		FBXW7_HUMAN (316-416): 1.38e-10: 65.1: 14.71