HitPredict

Interactor 1: EFTS (P43897)
Elongation factor Ts, mitochondrial (EF-Ts) (EF-TsMt)
Gene: TSFM

Interactor 2: IF2M (P46199)
Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt))
Gene: MTIF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	32877691, 28514442, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF_TS~GTP_EFTU
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005739 - mitochondrion
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 727
+	Hs
		799283 EFTS_HUMAN (1-313): 1.1e-160: 453: 100.00		GUF1_HUMAN (161-721): 3.59e-105: 337: 17.58
+	Hs
		799178 EFTS_HUMAN (1-313): 1.1e-160: 453: 100.00		EFTU_HUMAN (172-419): 7.3e-68: 232: 25.35
+	Bt
		799171 EFTS_BOVIN (12-325): 3.67e-148: 421: 83.84		EFTU_BOVIN (172-419): 1.66e-76: 255: 24.11
+	Dm
		1179843 EFTS_DROME (33-322): 4.51e-109: 321: 38.64		Q7K3V6_DROME (156-419): 5.97e-66: 227: 26.33
+	Ce
		105315 EFTS_CAEEL (45-316): 3.48e-85: 260: 32.55		G5ECM6_CAEEL (150-419): 2.51e-71: 242: 26.58
+	Ec
		458600 EFTS_ECOLI (45-325): 3.63e-75: 234: 25.84		EFTU1_ECOLI (172-419): 1.56e-78: 258: 24.82
+	Ec
		458601 EFTS_ECOLI (45-325): 3.63e-75: 234: 25.84		EFTU2_ECOLI (172-419): 1.53e-78: 258: 24.82
+	Mp
		618374 EFTS_MYCPN (44-325): 2.42e-82: 253: 26.32		EFTU_MYCPN (172-419): 2.52e-66: 226: 26.60
+	Bs
		702822 EFTS_BACSU (44-321): 9.09e-66: 210: 24.32		EFTU_BACSU (182-419): 1.45e-77: 256: 25.00
+	Ce
		106058 EFTS_CAEEL (45-316): 3.48e-85: 260: 32.55		G5EDF5_CAEEL (183-384): 6.4e-13: 73.6: 28.70