HitPredict

Interactor 1: VDAC2 (P45880)
Voltage-dependent anion-selective channel protein 2 (VDAC-2) (hVDAC2) (Outer mitochondrial membrane protein porin 2)
Gene: VDAC2

Interactor 2: TOM20 (Q15388)
Mitochondrial import receptor subunit TOM20 homolog (Mitochondrial 20 kDa outer membrane protein) (Outer mitochondrial membrane receptor Tom20)
Gene: TOMM20

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	29568061, 35271311
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0097225 - sperm midpiece
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 145
+	Hs
		601254 VDAC1_HUMAN (12-294): 1.42e-110: 323: 74.56		TOM20_HUMAN (1-145): 3e-70: 209: 100.00
+	Hs
		1072854 VDAC3_HUMAN (12-294): 1.21e-108: 318: 73.50		TOM20_HUMAN (1-145): 3e-70: 209: 100.00
+	Dm
		1277067 VDAC_DROME (15-294): 3.05e-106: 312: 62.14		Q95RF6_DROME (1-138): 8.62e-52: 163: 52.90
+	Hs
		330674 TOM40_HUMAN (12-290): 1.58e-72: 228: 12.63		TOM20_HUMAN (1-145): 3e-70: 209: 100.00
+	Sc
		389886 VDAC1_YEAST (14-294): 5.49e-80: 245: 23.59		TOM20_YEAST (4-123): 1.87e-43: 142: 27.34
+	Dm
		1278964 TO401_DROME (12-290): 5.41e-68: 216: 12.80		Q95RF6_DROME (1-138): 8.62e-52: 163: 52.90