HitPredict

Interactor 1: CBX5 (P45973)
Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Gene: CBX5

Interactor 2: ZNF45 (Q02386)
Zinc finger protein 45 (BRC1744) (Zinc finger protein 13) (Zinc finger protein KOX5)
Gene: ZNF45

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	20562864, 31403225
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 682
+	Hs
		1027143 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZN420_HUMAN (3-682): 0: 917: 47.45
+	Hs
		800409 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN569_HUMAN (1-663): 0: 857: 46.28
+	Hs
		800406 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		Z585B_HUMAN (45-662): 0: 815: 45.02
+	Hs
		983755 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZNF91_HUMAN (57-681): 0: 808: 44.96
+	Hs
		64135 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN729_HUMAN (49-677): 0: 783: 43.94
+	Hs
		1027081 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZN534_HUMAN (1-667): 0: 798: 43.76
+	Hs
		67424 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZN850_HUMAN (60-681): 0: 790: 46.30
+	Hs
		64140 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZN729_HUMAN (49-677): 0: 783: 43.94
+	Hs
		64138 CBX1_HUMAN (26-180): 2.32e-55: 175: 60.65		ZN729_HUMAN (49-677): 0: 783: 43.94
+	Hs
		64158 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN726_HUMAN (215-681): 0: 689: 53.53
+	Hs
		800447 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN227_HUMAN (50-582): 0: 688: 50.28
+	Hs
		800425 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		Z585A_HUMAN (49-578): 0: 684: 44.94
+	Hs
		728565 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZNF93_HUMAN (215-681): 0: 690: 52.03
+	Hs
		1027102 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZN227_HUMAN (50-582): 0: 688: 50.28
+	Hs
		1027217 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZN184_HUMAN (49-524): 0: 635: 41.25
+	Hs
		988824 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZN33A_HUMAN (49-526): 0: 608: 43.52
+	Hs
		970657 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZNF45_HUMAN (286-682): 0: 547: 59.45
+	Hs
		1027126 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZN615_HUMAN (371-682): 2.33e-139: 426: 51.28
+	Hs
		1027294 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZN226_HUMAN (49-262): 5.72e-58: 211: 26.15
+	Hs
		67855 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN724_HUMAN (49-193): 2.88e-27: 119: 18.12