HitPredict

Interactor 1: CBX5 (P45973)
Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Gene: CBX5

Interactor 2: ZN649 (Q9BS31)
Zinc finger protein 649
Gene: ZNF649

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	20562864
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 505
+	Hs
		800409 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN569_HUMAN (51-481): 0: 588: 38.04
+	Hs
		800402 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN568_HUMAN (73-486): 0: 583: 41.23
+	Hs
		1027027 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZN568_HUMAN (73-486): 0: 583: 41.23
+	Hs
		800406 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		Z585B_HUMAN (52-480): 0: 565: 39.82
+	Hs
		800425 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		Z585A_HUMAN (52-480): 0: 561: 39.59
+	Hs
		728565 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZNF93_HUMAN (49-484): 0: 566: 38.65
+	Hs
		200243 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN264_HUMAN (46-496): 0: 537: 35.14
+	Hs
		800464 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN614_HUMAN (1-475): 5.75e-136: 407: 44.52
+	Hs
		800508 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN577_HUMAN (10-492): 5.7e-114: 347: 44.33
+	Hs
		800500 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZIM3_HUMAN (1-454): 2.47e-108: 332: 42.16
+	Hs
		549158 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZN250_HUMAN (300-505): 6.29e-97: 305: 40.58
+	Hs
		800493 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN479_HUMAN (297-504): 3.6e-88: 281: 35.89
+	Hs
		64158 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN726_HUMAN (291-504): 5.72e-84: 273: 34.42
+	Hs
		1027000 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZN846_HUMAN (49-255): 1.37e-69: 233: 26.05
+	Hs
		800459 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZFP82_HUMAN (168-371): 2.72e-56: 197: 51.47
+	Hs
		58857 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		A2VDJ6_HUMAN (287-456): 2.28e-52: 186: 52.94
+	Hs
		800494 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN333_HUMAN (303-456): 6.59e-19: 92: 34.42
+	Hs
		800355 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN543_HUMAN (51-177): 9.73e-18: 88.2: 10.24
+	Hs
		67855 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN724_HUMAN (51-151): 2.93e-16: 83.6: 8.26
+	Hs
		563302 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZNF16_HUMAN (370-505): 8.18e-22: 100: 17.52