Protein: PLBL1
Phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1) (Phospholipase B domain-containing protein 1) [Cleaved into: Phospholipase B-like 1 chain A; Phospholipase B-like 1 chain B; Phospholipase B-like 1 chain C]

Gene: PLBL1, PLBD1
Organism: Homo sapiens
Interactions: 96
UniProt ID: Q6P4A8

Gene Ontology (top 5):
GO:0004620 - phospholipase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005764 - lysosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

391625

FRIH
Ferritin heavy chain

2

0

High-throughput

0.602

High

584556

VAV
Proto-oncogene vav

2

0

High-throughput

0.602

High

610722

TCPA
T-complex protein 1 subunit alpha

1

1

High-throughput

0.536

High

1007086

TCPB
T-complex protein 1 subunit beta

1

2

High-throughput

0.536

High

1242336

LIPB1
Liprin-beta-1

1

2

High-throughput

0.536

High

1242349

CTF18
Chromosome transmission fidelity protein 18 homolog

1

1

High-throughput

0.536

High

1242352

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

1

High-throughput

0.536

High

1242356

RNF31
E3 ubiquitin-protein ligase RNF31

1

2

High-throughput

0.536

High

1242361

TCPH
T-complex protein 1 subunit eta

1

1

High-throughput

0.536

High

1242377

NEMO
NF-kappa-B essential modulator

1

1

High-throughput

0.536

High

67475

ZSWM8
Zinc finger SWIM domain-containing protein 8

1

0

High-throughput

0.513

High

161726

APAF
Apoptotic protease-activating factor 1

1

0

High-throughput

0.513

High

177891

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

0

High-throughput

0.513

High

187528

FANCA
Fanconi anemia group A protein

1

0

High-throughput

0.513

High

188305

HDAC3
Histone deacetylase 3

1

0

High-throughput

0.513

High

292660

RENR
Renin receptor

1

0

High-throughput

0.513

High

343604

OXSR1
Serine/threonine-protein kinase OSR1

1

0

High-throughput

0.513

High

853702

MK08
Mitogen-activated protein kinase 8

1

0

High-throughput

0.513

High

873859

PCP4
Calmodulin regulator protein PCP4

1

0

High-throughput

0.513

High

888790

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

0

High-throughput

0.513

High

943072

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

983667

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.513

High

1023809

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.513

High

1129324

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

0

High-throughput

0.513

High

1142989

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.513

High

1187155

RGL3
Ral guanine nucleotide dissociation stimulator-like 3

1

0

High-throughput

0.513

High

1239222

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.513

High

1242334

BRAT1
Integrator complex assembly factor BRAT1

1

0

High-throughput

0.513

High

1242339

DAAF5
Dynein axonemal assembly factor 5

1

0

High-throughput

0.513

High

1242344

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

0

High-throughput

0.513

High

1242353

SYMPK
Symplekin

1

0

High-throughput

0.513

High

1242365

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1242367

TSSP
Thymus-specific serine protease

1

0

High-throughput

0.513

High

1242373

APC5
Anaphase-promoting complex subunit 5

1

0

High-throughput

0.513

High

602803

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.493

High

890511

RBP2
E3 SUMO-protein ligase RanBP2

1

0

High-throughput

0.493

High

1017437

FOXK1
Forkhead box protein K1

1

1

High-throughput

0.489

High

1029699

FOXK2
Forkhead box protein K2

1

1

High-throughput

0.489

High

1242366

ESRP2
Epithelial splicing regulatory protein 2

1

1

High-throughput

0.489

High

422352

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

849360

RANG
Ran-specific GTPase-activating protein

1

1

High-throughput

0.479

High

1242351

TCPW
T-complex protein 1 subunit zeta-2

1

2

High-throughput

0.479

High

583085

VATB1
V-type proton ATPase subunit B, kidney isoform

1

0

High-throughput

0.458

High

1219650

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

0

High-throughput

0.458

High

800506

VATA
V-type proton ATPase catalytic subunit A

1

1

High-throughput

0.445

High

839466

PI4KA
Phosphatidylinositol 4-kinase alpha

1

2

High-throughput

0.445

High

1195651

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

2

High-throughput

0.437

High

1043630

COAA1

1

0

High-throughput

0.426

High

1234825

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.426

High

1242345

PI4P1
Putative inactive phosphatidylinositol 4-kinase alpha-like protein P1

1

2

High-throughput

0.407

High

1242357

MITOK
Mitochondrial potassium channel

3

0

High-throughput

0.347

High

1242358

GMCL1
Germ cell-less protein-like 1

3

0

High-throughput

0.347

High

1156021

ZIC1
Zinc finger protein ZIC 1

2

0

High-throughput

0.328

High

1242342

SPICE
Spindle and centriole-associated protein 1

2

0

High-throughput

0.328

High

1242347

IL31R
Interleukin-31 receptor subunit alpha

2

0

High-throughput

0.328

High

1242368

TB22B
TBC1 domain family member 22B

2

0

High-throughput

0.328

High

1242370

GPT2L
G patch domain-containing protein 2-like

2

0

High-throughput

0.328

High

222374

TSN6
Tetraspanin-6

1

0

High-throughput

0.279

Low

252529

SEP15
Selenoprotein F

1

0

High-throughput

0.279

Low

298603

RAD17
Cell cycle checkpoint protein RAD17

1

0

High-throughput

0.279

Low

552280

ADT3
ADP/ATP translocase 3

1

0

High-throughput

0.279

Low

622824

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

0

High-throughput

0.279

Low

733377

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.279

Low

876348

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.279

Low

943481

DSCR6
Protein ripply3

1

0

High-throughput

0.279

Low

1060451

DPOE1
DNA polymerase epsilon catalytic subunit A

1

0

High-throughput

0.279

Low

1093470

COASY
Bifunctional coenzyme A synthase

1

0

High-throughput

0.279

Low

1094518

ZN154
Zinc finger protein 154

1

0

High-throughput

0.279

Low

1152914

NAB2
NGFI-A-binding protein 2

1

0

High-throughput

0.279

Low

1180145

QRIC1
Transcriptional regulator QRICH1

1

0

High-throughput

0.279

Low

1218545

SPO16
Protein SPO16 homolog

1

0

High-throughput

0.279

Low

1238214

GPAT2
Glycerol-3-phosphate acyltransferase 2, mitochondrial

1

0

High-throughput

0.279

Low

1242333

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

0

High-throughput

0.279

Low

1242337

MICU3
Calcium uptake protein 3, mitochondrial

1

0

High-throughput

0.279

Low

1242338

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.279

Low

1242340

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

0

High-throughput

0.279

Low

1242341

S35F2
Solute carrier family 35 member F2

1

0

High-throughput

0.279

Low

1242348

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.279

Low

1242350

ARAP3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

1

0

High-throughput

0.279

Low

1242354

NEIL2
Endonuclease 8-like 2

1

0

High-throughput

0.279

Low

1242355

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

1242359

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.279

Low

1242360

CABS1
Calcium-binding and spermatid-specific protein 1

1

0

High-throughput

0.279

Low

1242362

SH23A
SH2 domain-containing protein 3A

1

0

High-throughput

0.279

Low

1242363

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.279

Low

1242364

DCC1
Sister chromatid cohesion protein DCC1

1

0

High-throughput

0.279

Low

1242369

ABCF3
ATP-binding cassette sub-family F member 3

1

0

High-throughput

0.279

Low

1242374

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.279

Low

1242376

TF3C5
General transcription factor 3C polypeptide 5

1

0

High-throughput

0.279

Low

1242346

OR1N1
Olfactory receptor 1N1

1

0

High-throughput

0.269

Low

1114896

CUL4A
Cullin-4A

1

0

High-throughput

0.249

Low

1242335

PAQR2
Adiponectin receptor protein 2

1

0

Small-scale

0.249

Low

1242343

LSME2
Leucine-rich single-pass membrane protein 2

1

0

High-throughput

0.232

Low

1242371

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

0

High-throughput

0.232

Low

1242372

TCAL9
Transcription elongation factor A protein-like 9

1

0

High-throughput

0.232

Low

1242375

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025