HitPredict

Interactor 1: UBP5 (P45974)
Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5)
Gene: USP5

Interactor 2: TRI63 (Q969Q1)
E3 ubiquitin-protein ligase TRIM63 (EC 2.3.2.27) (Iris RING finger protein) (Muscle-specific RING finger protein 1) (MuRF-1) (MuRF1) (RING finger protein 28) (RING-type E3 ubiquitin transferase TRIM63) (Striated muscle RING zinc finger protein) (Tripartite motif-containing protein 63)
Gene: TRIM63

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	22626734
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008270 - zinc ion binding GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 858 Hs			1 353
+	Hs
		800622 UBP5_HUMAN (1-858): 0: 842: 100.00		TRI54_HUMAN (7-326): 7.72e-74: 234: 61.37
+	Hs
		800623 UBP5_HUMAN (1-858): 0: 842: 100.00		TRI55_HUMAN (11-324): 8.5e-72: 234: 61.78
+	Hs
		800631 UBP5_HUMAN (1-858): 0: 842: 100.00		TRI39_HUMAN (14-352): 5.49e-70: 229: 16.80
+	Hs
		800578 UBP5_HUMAN (1-858): 0: 842: 100.00		TRI26_HUMAN (8-353): 7.66e-66: 219: 14.60
+	Hs
		800626 UBP5_HUMAN (1-858): 0: 842: 100.00		TRIM8_HUMAN (15-330): 6.11e-65: 216: 20.87
+	Hs
		800627 UBP5_HUMAN (1-858): 0: 842: 100.00		TRIM5_HUMAN (10-346): 1.16e-64: 214: 17.49
+	Hs
		1273567 UBP13_HUMAN (2-858): 0: 721: 59.47		TRI63_HUMAN (1-326): 8.01e-81: 252: 100.00
+	Hs
		1273576 UBP13_HUMAN (2-858): 0: 721: 59.47		TRI55_HUMAN (11-324): 8.5e-72: 234: 61.78
+	Hs
		800594 UBP5_HUMAN (1-858): 0: 842: 100.00		TRI67_HUMAN (75-147): 2.92e-12: 69.8: 29.49
+	Hs
		1171098 UBP13_HUMAN (2-858): 0: 721: 59.47		TRI67_HUMAN (75-147): 2.92e-12: 69.8: 29.49
+	Hs
		1273778 UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17		TRI63_HUMAN (1-326): 8.01e-81: 252: 100.00
+	Hs
		1273788 UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17		TRI11_HUMAN (8-353): 1.23e-72: 234: 17.63
+	Hs
		1273851 UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17		TRI54_HUMAN (7-326): 7.72e-74: 234: 61.37
+	Hs
		1273852 UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17		TRI55_HUMAN (11-324): 8.5e-72: 234: 61.78
+	Hs
		1019375 UBP36_HUMAN (250-817): 9.73e-85: 295: 13.61		TRI26_HUMAN (8-353): 7.66e-66: 219: 14.60
+	Hs
		1223388 UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17		TRI22_HUMAN (16-347): 2.21e-69: 227: 17.94
+	Hs
		536961 UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17		TRI27_HUMAN (8-353): 1.89e-68: 225: 17.49
+	Hs
		1172289 UBP22_HUMAN (139-682): 5.21e-111: 352: 14.11		TRI67_HUMAN (75-147): 2.92e-12: 69.8: 29.49
+	Hs
		1171099 USP9X_HUMAN (289-758): 2.24e-84: 298: 16.20		TRI67_HUMAN (75-147): 2.92e-12: 69.8: 29.49
+	Hs
		1171100 UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17		TRI67_HUMAN (75-147): 2.92e-12: 69.8: 29.49