HitPredict

Interactor 1: UBP5 (P45974)
Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5)
Gene: USP5

Interactor 2: TRIM5 (Q9C035)
Tripartite motif-containing protein 5 (EC 2.3.2.27) (RING finger protein 88) (RING-type E3 ubiquitin transferase TRIM5)
Gene: TRIM5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	23105109
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 858 Hs			1 493
+	Hs
		800631 UBP5_HUMAN (1-858): 0: 842: 100.00		TRI39_HUMAN (6-492): 6.9e-127: 381: 27.48
+	Hs
		800578 UBP5_HUMAN (1-858): 0: 842: 100.00		TRI26_HUMAN (1-490): 4.61e-103: 320: 25.73
+	Hs
		800600 UBP5_HUMAN (1-858): 0: 842: 100.00		TRIML_HUMAN (2-493): 7.91e-101: 312: 25.10
+	Hs
		1121195 UBP39_HUMAN (133-660): 1.38e-83: 280: 14.87		TRIM5_HUMAN (1-493): 3.88e-147: 432: 100.00
+	Hs
		1223388 UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17		TRI22_HUMAN (1-493): 8.67e-130: 387: 50.98
+	Hs
		1121201 UBP39_HUMAN (133-660): 1.38e-83: 280: 14.87		TRI39_HUMAN (6-492): 6.9e-127: 381: 27.48
+	Hs
		1273788 UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17		TRI11_HUMAN (2-491): 2.14e-121: 365: 31.91
+	Hs
		536961 UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17		TRI27_HUMAN (1-492): 5.51e-121: 365: 29.21
+	Hs
		1019375 UBP36_HUMAN (250-817): 9.73e-85: 295: 13.61		TRI26_HUMAN (1-490): 4.61e-103: 320: 25.73
+	Hs
		1019313 UBP39_HUMAN (133-660): 1.38e-83: 280: 14.87		TRI26_HUMAN (1-490): 4.61e-103: 320: 25.73
+	Hs
		1273967 UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17		TRI35_HUMAN (2-491): 7.11e-93: 292: 21.40
+	Hs
		1318717 UBP21_HUMAN (319-594): 6.55e-24: 109: 22.37		TRIM5_HUMAN (1-493): 3.88e-147: 432: 100.00
+	Hs
		271189 UBP2_HUMAN (700-854): 1.43e-11: 70.1: 16.05		TRIM5_HUMAN (1-493): 3.88e-147: 432: 100.00
+	Hs
		271032 UBP2_HUMAN (700-854): 1.43e-11: 70.1: 16.05		RO52_HUMAN (1-492): 6.35e-136: 402: 39.80
+	Hs
		271195 UBP2_HUMAN (700-854): 1.43e-11: 70.1: 16.05		TRI39_HUMAN (6-492): 6.9e-127: 381: 27.48
+	Hs
		271027 UBP2_HUMAN (700-854): 1.43e-11: 70.1: 16.05		TRI27_HUMAN (1-492): 5.51e-121: 365: 29.21
+	Hs
		1273857 UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17		TRI31_HUMAN (1-269): 5.66e-40: 150: 31.25
+	Hs
		271184 UBP2_HUMAN (700-854): 1.43e-11: 70.1: 16.05		TRI34_HUMAN (1-493): 9.36e-114: 346: 55.75
+	Hs
		271136 UBP2_HUMAN (700-854): 1.43e-11: 70.1: 16.05		TRI50_HUMAN (5-481): 4.35e-98: 306: 24.74
+	Hs
		1173835 UBP49_HUMAN (177-293): 1.05e-15: 83.7: 26.50		TRI35_HUMAN (2-491): 7.11e-93: 292: 21.40