HitPredict

Interactor 1: KI67 (P46013)
Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67) (Antigen KI-67) (Antigen Ki67)
Gene: MKI67

Interactor 2: H2B1D (P58876)
Histone H2B type 1-D (H2B-clustered histone 5) (HIRA-interacting protein 2) (Histone H2B.1 B) (Histone H2B.b) (H2B/b)
Gene: H2BC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3256 Hs			1 126
+	Hs
		801169 KI67_HUMAN (1-3256): 0: 1046: 100.00		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		801063 KI67_HUMAN (1-3256): 0: 1046: 100.00		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		801337 KI67_HUMAN (1-3256): 0: 1046: 100.00		H2B1L_HUMAN (1-126): 3.72e-52: 162: 97.62
+	Hs
		1056847 MDC1_HUMAN (20-1865): 6.71e-101: 366: 9.14		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		1056919 MDC1_HUMAN (20-1865): 6.71e-101: 366: 9.14		H2B1H_HUMAN (1-126): 8.88e-54: 166: 98.41
+	Hs
		707631 MDC1_HUMAN (20-1865): 6.71e-101: 366: 9.14		H2B1B_HUMAN (1-126): 1.77e-53: 165: 97.62
+	Hs
		918364 MDC1_HUMAN (20-1865): 6.71e-101: 366: 9.14		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		807749 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		H2B2F_HUMAN (1-126): 3.9e-54: 167: 97.62
+	Hs
		807817 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		H2B1M_HUMAN (1-126): 4.45e-54: 167: 96.83
+	Hs
		420812 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		H2B1J_HUMAN (1-126): 1.25e-53: 166: 97.62
+	Hs
		617932 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		H2B1O_HUMAN (1-126): 5.42e-54: 166: 97.62
+	Hs
		807743 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		807795 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		H2B1H_HUMAN (1-126): 8.88e-54: 166: 98.41
+	Hs
		241473 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		H2B1K_HUMAN (1-126): 2.11e-53: 165: 98.41
+	Hs
		707546 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		H2B1B_HUMAN (1-126): 1.77e-53: 165: 97.62
+	Hs
		807658 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		H2B1D_HUMAN (1-126): 2.74e-53: 165: 100.00
+	Hs
		807677 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		807816 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		H2B1N_HUMAN (1-126): 3.49e-53: 164: 99.21
+	Hs
		807818 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		H2B1L_HUMAN (1-126): 3.72e-52: 162: 97.62
+	Hs
		807775 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		H2B3B_HUMAN (1-126): 2.67e-51: 160: 95.24