HitPredict

Interactor 1: RECQ1 (P46063)
ATP-dependent DNA helicase Q1 (EC 5.6.2.4) (DNA 3'-5' helicase Q1) (DNA helicase, RecQ-like type 1) (RecQ1) (DNA-dependent ATPase Q1) (RecQ protein-like 1)
Gene: RECQL

Interactor 2: FOXC1 (Q12948)
Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead-related transcription factor 3) (FREAC-3)
Gene: FOXC1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	25609649, 34551306
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 649 Hs			1 553
+	Hs
		1021140 DDX17_HUMAN (8-505): 7.91e-129: 398: 14.54		FOXC1_HUMAN (1-553): 8.84e-82: 267: 100.00
+	Hs
		801864 RECQ1_HUMAN (1-649): 1.14e-156: 467: 100.00		FOXO1_HUMAN (50-463): 3.5e-45: 171: 18.76
+	Hs
		126443 RECQ1_HUMAN (1-649): 1.14e-156: 467: 100.00		FOXE1_HUMAN (54-390): 3.86e-46: 167: 31.66
+	Hs
		801902 RECQ1_HUMAN (1-649): 1.14e-156: 467: 100.00		FOXI2_HUMAN (47-287): 5.12e-46: 165: 34.02
+	Hs
		801835 RECQ1_HUMAN (1-649): 1.14e-156: 467: 100.00		FOXA1_HUMAN (14-357): 6.54e-35: 139: 30.52
+	Hs
		571418 DDX5_HUMAN (9-468): 1.14e-125: 386: 15.97		FOXO1_HUMAN (50-463): 3.5e-45: 171: 18.76
+	Hs
		294595 RECQ4_HUMAN (76-453): 5.17e-127: 405: 30.39		FOXL2_HUMAN (30-287): 7.53e-38: 145: 30.62
+	Hs
		294774 RECQ4_HUMAN (76-453): 5.17e-127: 405: 30.39		FOXD4_HUMAN (18-412): 2.13e-34: 137: 26.77
+	Hs
		877790 DDX42_HUMAN (2-458): 4.83e-115: 368: 14.44		FOXA1_HUMAN (14-357): 6.54e-35: 139: 30.52