Protein: VHS1
Serine/threonine-protein kinase VHS1 (EC 2.7.11.1) (Viable in a HAL3 SIT4 background protein 1)

Gene: VHS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 72
UniProt ID: Q03785

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

793368

PP2C4
Protein phosphatase 2C homolog 4

3

16

High-throughput

0.861

High

757635

SIP2
SNF1 protein kinase subunit beta-2

1

18

High-throughput

0.724

High

475138

CYAA
Adenylate cyclase

1

7

High-throughput

0.691

High

1026816

CDC14
Tyrosine-protein phosphatase CDC14

1

4

High-throughput

0.691

High

757995

SEF1
Putative transcription factor SEF1

3

1

High-throughput

0.670

High

454759

KAPR
cAMP-dependent protein kinase regulatory subunit

1

2

High-throughput

0.647

High

793200

AKL1
Serine/threonine-protein kinase AKL1

1

19

High-throughput

0.647

High

803207

RIM4
Meiotic activator RIM4

1

2

High-throughput

0.647

High

1043534

SKY1
Serine/threonine-protein kinase SKY1

1

10

High-throughput

0.647

High

1044078

RGC1
Regulator of the glycerol channel 1

2

2

High-throughput

0.619

High

789814

SOL2
6-phosphogluconolactonase-like protein 2

2

3

Small-scale

0.602

High

820889

SIP5
Protein SIP5

2

1

Small-scale

0.602

High

1025023

NUM1
Nuclear migration protein NUM1

2

4

High-throughput

0.574

High

824698

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

3

High-throughput

0.561

High

865348

3HAO
3-hydroxyanthranilate 3,4-dioxygenase

1

1

High-throughput

0.561

High

819676

SSB2
Ribosome-associated molecular chaperone SSB2

2

5

High-throughput

0.552

High

722226

XPO1
Exportin-1

1

3

High-throughput

0.536

High

743281

PP12
Serine/threonine-protein phosphatase PP1-2

1

3

High-throughput

0.536

High

828618

YAP4
AP-1-like transcription factor YAP4

1

1

High-throughput

0.536

High

844345

ELP2
Elongator complex protein 2

1

3

High-throughput

0.536

High

871505

ASK10
Activator of SKN7 protein 10

1

2

High-throughput

0.536

High

1026966

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

11

High-throughput

0.536

High

1044075

SYF1
Pre-mRNA-splicing factor SYF1

1

1

High-throughput

0.536

High

1044085

BMS1
Ribosome biogenesis protein BMS1

1

1

High-throughput

0.536

High

444794

SIR2
NAD-dependent histone deacetylase SIR2

1

0

High-throughput

0.513

High

597635

MER1
Meiotic recombination 1 protein

1

0

High-throughput

0.513

High

645583

MSN1
Protein MSN1

1

0

High-throughput

0.513

High

735296

IMPX
Sugar utilization regulatory protein IMP2

1

0

High-throughput

0.513

High

795967

RRN10
RNA polymerase I-specific transcription initiation factor RRN10

1

0

High-throughput

0.513

High

818671

FTHC
5-formyltetrahydrofolate cyclo-ligase

1

0

High-throughput

0.513

High

893096

YG51
Uncharacterized protein YGR237C

1

0

High-throughput

0.513

High

920935

RRN9
RNA polymerase I-specific transcription initiation factor RRN9

1

0

High-throughput

0.513

High

1039689

ELP3
Elongator complex protein 3

1

0

High-throughput

0.513

High

1044076

LRS4
Monopolin complex subunit LRS4

1

0

High-throughput

0.513

High

1044079

ELP1
Elongator complex protein 1

1

0

High-throughput

0.513

High

1044088

PAA1
Polyamine N-acetyltransferase 1

1

0

High-throughput

0.513

High

1044081

ACK1
Activator of C kinase protein 1

1

3

High-throughput

0.512

High

638039

UTR1
NAD(+) kinase

1

1

High-throughput

0.501

High

780163

SDS22
Protein phosphatase 1 regulatory subunit SDS22

1

4

High-throughput

0.501

High

795992

NCL1
Multisite-specific tRNA:(cytosine-C(5))-methyltransferase

1

3

High-throughput

0.501

High

824536

6P21
6-phosphofructo-2-kinase 1

1

4

High-throughput

0.501

High

830249

ARF3
ADP-ribosylation factor 3

1

3

High-throughput

0.501

High

866187

MET7
Cystathionine gamma-synthase

1

2

High-throughput

0.501

High

894392

SOL1
6-phosphogluconolactonase-like protein 1

1

3

High-throughput

0.501

High

916831

MGA1
Protein MGA1

1

4

High-throughput

0.501

High

917121

STR3
Cystathionine beta-lyase

1

2

High-throughput

0.501

High

1044077

YM11A
Transposon Ty1-ML1 Gag polyprotein

1

12

High-throughput

0.501

High

1044082

CMS1
Protein CMS1

1

1

High-throughput

0.501

High

1044089

RKM4
Ribosomal lysine N-methyltransferase 4

1

1

High-throughput

0.501

High

680025

CDC48
Cell division control protein 48

1

5

High-throughput

0.500

High

739754

SPT16
FACT complex subunit SPT16

1

2

High-throughput

0.489

High

757950

SKT5
Chitin synthase regulator SKT5

1

3

High-throughput

0.489

High

825773

MAM33
Mitochondrial acidic protein MAM33

1

3

High-throughput

0.489

High

864321

NET1
Nucleolar protein NET1

1

2

High-throughput

0.489

High

1035371

TOF2
Topoisomerase 1-associated factor 2

1

2

High-throughput

0.489

High

804141

PANE
2-dehydropantoate 2-reductase

1

0

High-throughput

0.480

High

1044080

DIB1
Spliceosomal protein DIB1

1

0

High-throughput

0.480

High

1044084

MPC54
Meiotic plaque component protein 54

1

0

High-throughput

0.480

High

1044087

YD177
IMPACT family member YDL177C

1

0

High-throughput

0.480

High

644978

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

1

High-throughput

0.479

High

680613

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

2

High-throughput

0.479

High

864819

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.479

High

1044086

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

10

High-throughput

0.479

High

745197

CDC13
Cell division control protein 13

1

2

High-throughput

0.457

High

850345

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

7

High-throughput

0.457

High

405135

LEU3
3-isopropylmalate dehydrogenase

1

2

High-throughput

0.457

High

678896

CSM1
Monopolin complex subunit CSM1

1

0

High-throughput

0.279

Low

874291

MRX6
MIOREX complex component 6

1

0

High-throughput

0.279

Low

1044083

RCL1
rRNA processing protein RCL1

1

0

High-throughput

0.279

Low

659163

MBR1
Mitochondrial biogenesis regulation protein 1

1

0

High-throughput

0.261

Low

782054

FMP46
Putative redox protein FMP46, mitochondrial

1

0

High-throughput

0.261

Low

64278

YP010
UPF0495 protein YPR010C-A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025