HitPredict

Interactor 1: 5HT3A (P46098)
5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)
Gene: HTR3A

Interactor 2: LEMD2 (Q8NC56)
LEM domain-containing protein 2 (hLEM2)
Gene: LEMD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 478 Hs			1 503
+	Hs
		687005 ACHA3_HUMAN (30-476): 0: 530: 22.69		LEMD2_HUMAN (1-503): 0: 732: 100.00
+	Hs
		677154 ACHB4_HUMAN (8-478): 2.26e-174: 500: 25.30		LEMD2_HUMAN (1-503): 0: 732: 100.00
+	Hs
		985144 ACHB3_HUMAN (12-478): 4.05e-166: 478: 25.75		LEMD2_HUMAN (1-503): 0: 732: 100.00
+	Hs
		1241121 ACHA9_HUMAN (4-469): 2.47e-154: 449: 27.29		LEMD2_HUMAN (1-503): 0: 732: 100.00
+	Hs
		506336 ACHB_HUMAN (31-470): 1.94e-148: 434: 23.62		LEMD2_HUMAN (1-503): 0: 732: 100.00
+	Hs
		362164 ACHA_HUMAN (14-469): 1.65e-159: 461: 25.27		MAN1_HUMAN (199-500): 3.95e-153: 461: 37.05
+	Hs
		798533 ACHA4_HUMAN (355-475): 1.85e-27: 117: 19.01		LEMD2_HUMAN (1-503): 0: 732: 100.00
+	Hs
		1263284 5HT3C_HUMAN (46-473): 3.65e-88: 278: 37.59		MAN1_HUMAN (199-500): 3.95e-153: 461: 37.05