Protein: D5SHR3
HECT-type E3 ubiquitin transferase (EC 2.3.2.26)

Gene: D5SHR3, Hecw
Organism: Drosophila melanogaster
Interactions: 38
UniProt ID: D5SHR3

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0009966 - regulation of signal transduction
GO:0016567 - protein ubiquitination
GO:0016874 - ligase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

94225

UBIQP
Polyubiquitin [Cleaved into: Ubiquitin]

1

20

High-throughput

0.621

High

94226

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

16

High-throughput

0.621

High

94228

FAS2
Fasciclin-2

2

5

High-throughput

0.584

High

94227

BIP
Endoplasmic reticulum chaperone BiP

1

13

High-throughput

0.481

High

94229

UCHL
Ubiquitin carboxyl-terminal hydrolase

1

4

High-throughput

0.481

High

94233

TBB1
Tubulin beta-1 chain

1

12

High-throughput

0.481

High

94244

EF1G
Elongation factor 1-gamma

1

7

High-throughput

0.481

High

94241

Q8SYU5
RE33762p

1

20

High-throughput

0.479

High

94243

Q9I7L0
LP01847p

1

20

High-throughput

0.479

High

94248

Q9VGU4
FI02822p

1

20

High-throughput

0.479

High

94249

Q9VHZ7
LD29844p

1

20

High-throughput

0.479

High

94250

Q9VI00
FI24305p1

1

20

High-throughput

0.479

High

94235

Q29QY7
IP15859p

1

1

High-throughput

0.451

High

2

A0A021WW64
Uncharacterized protein, isoform G

1

1

High-throughput

0.439

High

58533

A1ZBU8
Uncharacterized protein, isoform A

1

1

High-throughput

0.439

High

84611

B7Z028
Acyl-coenzyme A oxidase

1

2

High-throughput

0.439

High

94222

M9PE30
Transgelin

1

8

High-throughput

0.439

High

94223

RL3
Large ribosomal subunit protein uL3

1

5

High-throughput

0.439

High

94224

HMIN
Homeobox protein invected

1

3

High-throughput

0.439

High

94230

RL7A
Large ribosomal subunit protein eL8

1

9

High-throughput

0.439

High

94231

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.439

High

94232

RS3A
Small ribosomal subunit protein eS1

1

5

High-throughput

0.439

High

94234

PHYL
Protein phyllopod

1

1

High-throughput

0.439

High

94237

Q7KS72
C15

1

3

High-throughput

0.439

High

94238

Q7KUK4
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

94239

Q86BG3
Uncharacterized protein, isoform A

1

1

High-throughput

0.439

High

94240

Q8STI6
RE53401p

1

1

High-throughput

0.439

High

94242

GLYR1
Cytokine-like nuclear factor N-PAC

1

4

High-throughput

0.439

High

94245

Q9U622
GH25507p

1

3

High-throughput

0.439

High

94246

PTC71
Protein phosphatase PTC7 homolog fig

1

1

High-throughput

0.439

High

94247

FLNA
Filamin-A

1

15

High-throughput

0.439

High

94251

Q9VP13
Large ribosomal subunit protein mL64

1

2

High-throughput

0.439

High

94253

Q9VU59
GEO07864p1

1

1

High-throughput

0.439

High

94254

Q9VW52
Precursor RNA processing 3, isoform A

1

1

High-throughput

0.439

High

94255

Q9VXS4
Uncharacterized protein, isoform A

1

1

High-throughput

0.439

High

94256

Q9W229
40S ribosomal protein S24

1

4

High-throughput

0.439

High

94236

Q4V4P1
IP04230p

2

0

High-throughput

0.310

High

94252

Q9VQ58
BRCA2-interacting transcriptional repressor EMSY

2

0

High-throughput

0.310

High


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Last updated: 11Aug2025