Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK
Interactor 2: DOCK1 (Q14185)
Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180)
Gene: DOCK1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.980 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12615911, 10559471, 31980649, 8657152, 11369773, 8662907, 33961781, 35044719, 15700267, 15673687, 17515907, 17474147, unassigned2173 |
| Identification Methods | affinity chromatography technology, pull down, unspecified method, anti tag coimmunoprecipitation, peptide array, phage display |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SH2~SH3_1, SH3_1~SH3_1, DOCK_N~SH3_2, SH3_1~SH3_2 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0016477 - cell migration and 2 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
