Interactor 1: CRKL (P46109)
Crk-like protein
Gene: CRKL
Interactor 2: ARHG5 (Q12774)
Rho guanine nucleotide exchange factor 5 (Ephexin-3) (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (Transforming immortalized mammary oncogene) (p60 TIM)
Gene: ARHGEF5
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.67 | 1.00 | 0.821 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32203420, 21988832, unassigned2213 |
| Identification Methods | affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SH2~SH3_1, PH~SH3_1, RhoGEF~SH3_1, SH3_1~SH3_1, SH3_1~SH3_2 |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0035556 - intracellular signal transduction |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
