HitPredict

Interactor 1: MTHR1 (P46151)
Methylenetetrahydrofolate reductase 1 (EC 1.5.1.20)
Gene: MET12

Interactor 2: MTHR2 (P53128)
Methylenetetrahydrofolate reductase 2 (EC 1.5.1.53) (YmL45)
Gene: MET13

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.848

The method score is based on:

Property Details
Experiments 16554755, 16429126, 20826334
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MTHFR~MTHFR
Common GO terms GO:0004489 - methylenetetrahydrofolate reductase (NAD(P)H) activity
GO:0005829 - cytosol
GO:0009086 - methionine biosynthetic process
GO:0035999 - tetrahydrofolate interconversion
GO:0071949 - FAD binding
and 1 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 657
Sc

1 600
+ Sp
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024