HitPredict

Interactor 1: BAG6 (P46379)
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)
Gene: BAG6

Interactor 2: L2GL2 (Q6P1M3)
LLGL scribble cell polarity complex component 2 (HGL) (Lethal(2) giant larvae protein homolog 2)
Gene: LLGL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1132 Hs			1 1020
+	Hs
		803547 BAG6_HUMAN (1-1132): 0: 597: 100.00		PWP2_HUMAN (28-330): 1.35e-64: 237: 15.46
+	Hs
		803475 BAG6_HUMAN (1-1132): 0: 597: 100.00		WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50
+	Hs
		903105 RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72		WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50
+	Hs
		903374 KMT2C_HUMAN (269-805): 1.24e-13: 78.2: 9.11		WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50
+	Mm
		903669 KMT2C_MOUSE (278-784): 7.88e-12: 72.5: 10.78		WDR5_MOUSE (29-216): 7.81e-21: 96.9: 12.50
+	Hs
		903405 CBP_HUMAN (204-749): 1.19e-09: 65.1: 12.25		WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50