HitPredict

Interactor 1: BAG6 (P46379)
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)
Gene: BAG6

Interactor 2: H2A1C (Q93077)
Histone H2A type 1-C (H2A-clustered histone 6) (Histone H2A/l)
Gene: H2AC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1132 Hs			1 130
+	Hs
		391610 SC24C_HUMAN (380-696): 1.27e-39: 162: 24.18		H2A1B_HUMAN (1-130): 1.52e-67: 201: 98.46
+	Mm
		101453 F8VPR5_MOUSE (128-733): 2.34e-33: 142: 12.70		H2A3_MOUSE (1-130): 1.07e-67: 201: 99.23
+	Hs
		554260 MUC1_HUMAN (122-783): 1.91e-30: 132: 11.94		H2AX_HUMAN (1-130): 1.1e-63: 192: 89.55
+	Hs
		391924 UBQL4_HUMAN (6-549): 7.75e-26: 115: 11.19		H2A1B_HUMAN (1-130): 1.52e-67: 201: 98.46
+	Hs
		924034 RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72		H2A2A_HUMAN (1-130): 9.4e-68: 202: 98.46
+	Hs
		924322 RL40_HUMAN (17-87): 9.53e-28: 111: 34.72		H2A2A_HUMAN (1-130): 9.4e-68: 202: 98.46
+	Hs
		924374 RL40_HUMAN (17-87): 9.53e-28: 111: 34.72		H2A1C_HUMAN (1-130): 9.61e-68: 202: 100.00
+	Hs
		391643 RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72		H2A1B_HUMAN (1-130): 1.52e-67: 201: 98.46
+	Hs
		391644 RL40_HUMAN (17-87): 9.53e-28: 111: 34.72		H2A1B_HUMAN (1-130): 1.52e-67: 201: 98.46
+	Hs
		470331 RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72		H2A1_HUMAN (1-130): 1.29e-67: 201: 98.46
+	Hs
		470332 RL40_HUMAN (17-87): 9.53e-28: 111: 34.72		H2A1_HUMAN (1-130): 1.29e-67: 201: 98.46
+	Hs
		924049 RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72		H2A3_HUMAN (1-130): 1.07e-67: 201: 99.23
+	Hs
		924334 RL40_HUMAN (17-87): 9.53e-28: 111: 34.72		H2A3_HUMAN (1-130): 1.07e-67: 201: 99.23
+	Hs
		924397 RL40_HUMAN (17-87): 9.53e-28: 111: 34.72		H2A1J_HUMAN (1-128): 5.32e-67: 200: 97.66
+	Hs
		924387 RL40_HUMAN (17-87): 9.53e-28: 111: 34.72		H2A1H_HUMAN (1-128): 7.48e-67: 199: 98.44
+	Hs
		1312243 UBQL1_HUMAN (15-521): 2.36e-25: 114: 12.84		H2AJ_HUMAN (1-126): 8.72e-65: 194: 96.03
+	Hs
		555403 RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72		H2AX_HUMAN (1-130): 1.1e-63: 192: 89.55
+	Hs
		555404 RL40_HUMAN (17-87): 9.53e-28: 111: 34.72		H2AX_HUMAN (1-130): 1.1e-63: 192: 89.55
+	Sc
		392251 RL40A_YEAST (17-87): 6.63e-27: 108: 34.72		H2A2_YEAST (16-128): 3.45e-59: 180: 81.42
+	Hs
		391802 KMT2C_HUMAN (269-805): 1.24e-13: 78.2: 9.11		H2A1B_HUMAN (1-130): 1.52e-67: 201: 98.46