Interactor 1: CIC1 (P38779)
Proteasome-interacting protein CIC1 (Core interacting component 1)
Gene: CIC1

Interactor 2: NOP15 (P53927)
Ribosome biogenesis protein 15 (Nucleolar protein 15)
Gene: NOP15

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.753

The method score is based on:

Property Details
Experiments 11805826, 12374754, 16429126, 18467557, 37968396, 31851481, 24129494, 16554755, 17922018
Identification Methods tandem affinity purification, affinity chromatography technology, protein complementation assay, cross-linking study, two hybrid, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005730 - nucleolus
GO:0006364 - rRNA processing
GO:0019843 - rRNA binding
and 3 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 376
Sc

1 220
+ Hs
+ Sc
+ Hs
+ Dm

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Last updated: 11Aug2025