HitPredict

Interactor 1: CDN1B (P46527)
Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1)
Gene: CDKN1B

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 0.60 0.634

The method score is based on:

Property Details
Experiments 23333463, 19470470
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
GO:0030334 - regulation of cell migration
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 198
Hs

1 193
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024