Protein: GIC2
GTPase-interacting component 2

Gene: GIC2
Organism: Saccharomyces cerevisiae S288C
Interactions: 50
UniProt ID: Q06648

Gene Ontology (top 5):
GO:0000131 - incipient cellular bud site
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane
GO:0005934 - cellular bud tip

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

618363

CDC42
Cell division control protein 42

11

1

Small-scale

0.757

High

737343

CDC12
Cell division control protein 12

4

1

Small-scale

0.689

High

672467

STE50
Protein STE50

3

1

High-throughput

0.639

High

804098

GIC1
GTPase-interacting component 1

3

1

High-throughput

0.639

High

874268

CLA4
Serine/threonine-protein kinase CLA4

3

1

High-throughput

0.639

High

932300

ZDS2
Protein ZDS2

3

3

High-throughput

0.639

High

760362

BMH2
Protein BMH2

2

1

Small-scale

0.600

High

678900

CSM1
Monopolin complex subunit CSM1

3

1

High-throughput

0.583

High

780712

RRP14
Ribosomal RNA-processing protein 14

3

1

High-throughput

0.583

High

364762

CDK1
Cyclin-dependent kinase 1

2

0

Small-scale

0.577

High

737120

CDC11
Cell division control protein 11

1

2

Small-scale

0.573

High

809163

GDS1
GTPase-GDP dissociation stimulator BEM4

2

1

High-throughput

0.565

High

1050271

DFG5
Mannan endo-1,6-alpha-mannosidase DFG5

2

1

High-throughput

0.565

High

703784

CAPZA
F-actin-capping protein subunit alpha

2

0

High-throughput

0.565

High

811278

RGA1
Rho-type GTPase-activating protein 1

2

0

High-throughput

0.565

High

686906

BUB2
Mitotic check point protein BUB2

2

1

High-throughput

0.516

High

893436

ZDS1
Protein ZDS1

1

3

High-throughput

0.508

High

709471

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.480

High

580129

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

710003

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

737052

CDC3
Cell division control protein 3

1

1

Small-scale

0.479

High

542992

CDC24
Cell division control protein 24

1

0

Small-scale

0.460

High

818528

PEA2
Protein PEA2

1

0

Small-scale

0.460

High

835554

BUD6
Bud site selection protein 6

1

0

Small-scale

0.460

High

836343

BNI1
Protein BNI1

1

0

Small-scale

0.458

High

1056376

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

809064

POP2
Poly(A) ribonuclease POP2

1

1

High-throughput

0.457

High

393396

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

525277

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

819902

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

963742

H3
Histone H3

1

1

High-throughput

0.437

High

438167

NOT2
General negative regulator of transcription subunit 2

1

1

High-throughput

0.417

High

553931

WHI2
Growth regulation protein

1

1

High-throughput

0.417

High

816677

YEA8
Uncharacterized protein YEL008W

1

1

High-throughput

0.417

High

917960

GEP7
Genetic interactor of prohibitin 7, mitochondrial

1

1

High-throughput

0.417

High

1056377

GIS3
Protein GIS3

1

1

High-throughput

0.417

High

666710

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

2

0

Small-scale

0.306

High

441267

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.261

Low

509733

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

0

High-throughput

0.261

Low

708292

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

764161

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

805363

UBA4
Adenylyltransferase and sulfurtransferase UBA4

1

0

Small-scale

0.249

Low

826868

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

1053976

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

816644

NPP2
Ectonucleotide pyrophosphatase/phosphodiesterase 2

1

0

High-throughput

0.238

Low

823213

NTA1
Protein N-terminal amidase

1

0

High-throughput

0.238

Low

1044254

PKR1
V-type ATPase assembly factor PKR1

1

0

High-throughput

0.238

Low

1046860

RM01
Large ribosomal subunit protein uL1m

1

0

High-throughput

0.238

Low

824564

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.232

Low

865969

DPH4
Diphthamide biosynthesis protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025