Interactor 1: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1

Interactor 2: CNTN1 (Q12860)
Contactin-1 (Glycoprotein gp135) (Neural cell surface protein F3)
Gene: CNTN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 14567914
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~I-set, Ank_2~fn3, Ank_2~I-set, EGF_CA~fn3
Common GO terms GO:0005886 - plasma membrane
GO:0007219 - Notch signaling pathway
GO:0007411 - axon guidance
GO:0010628 - positive regulation of gene expression
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 2555
Hs

1 1018
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs

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Last updated: 15 Jul 2024