HitPredict

Interactor 1: AIP1 (P46680)
Actin-interacting protein 1
Gene: AIP1

Interactor 2: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	1.00	0.934

Property	Details
Experiments	10366597, 7719850, 17483419, 16611742, 16421248, 18719252
Identification Methods	two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Actin~WD40
Common GO terms	GO:0005634 - nucleus GO:0005884 - actin filament GO:0030479 - actin cortical patch
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 615 Sc			1 375
+	Hs
		254068 WDR1_HUMAN (4-613): 1.14e-114: 356: 25.90		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		254073 WDR1_HUMAN (4-613): 1.14e-114: 356: 25.90		ACTG_HUMAN (1-375): 0: 600: 89.07
+	At
		862532 AIP12_ARATH (4-613): 4.3e-94: 303: 26.72		ACT7_ARATH (3-375): 0: 646: 84.18
+	Hs
		254075 WDR1_HUMAN (4-613): 1.14e-114: 356: 25.90		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		903280 WDR5_HUMAN (474-614): 7.89e-32: 127: 16.20		ACTBL_HUMAN (2-375): 0: 687: 83.42
+	Hs
		792947 LIS1_HUMAN (427-615): 1.12e-35: 140: 16.15		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		792968 LIS1_HUMAN (427-615): 1.12e-35: 140: 16.15		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Hs
		891660 WDR5_HUMAN (474-614): 7.89e-32: 127: 16.20		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		903110 WDR5_HUMAN (474-614): 7.89e-32: 127: 16.20		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Dm
		950128 WDR1_DROME (414-615): 2.76e-23: 106: 14.15		ACT6_DROME (2-375): 0: 593: 87.97
+	Dm
		361195 WDR1_DROME (414-615): 2.76e-23: 106: 14.15		ACT4_DROME (2-375): 0: 587: 86.63
+	Hs
		932318 SNR40_HUMAN (449-612): 1.68e-12: 71: 16.36		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		932189 SMU1_HUMAN (444-612): 4.53e-11: 67.5: 18.64		ACTC_HUMAN (2-375): 0: 591: 87.17