Protein: AP1G1
AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)

Gene: AP1G1
Organism: Homo sapiens
Interactions: 124
UniProt ID: O43747

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005518 - collagen binding
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0005769 - early endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

225791

AP1S2
AP-1 complex subunit sigma-2

7

20

Small-scale

0.972

High

225805

AP1B1
AP-1 complex subunit beta-1

6

15

Small-scale

0.938

High

225794

AP1S1
AP-1 complex subunit sigma-1A

6

20

Small-scale

0.932

High

225845

AP2M1
AP-2 complex subunit mu

5

20

Small-scale

0.922

High

225869

AP1M2
AP-1 complex subunit mu-2

4

20

Small-scale

0.895

High

225856

NECP2
Adaptin ear-binding coat-associated protein 2

3

12

Small-scale

0.847

High

225800

CLH1
Clathrin heavy chain 1

3

9

Small-scale

0.829

High

225852

AP1M1
AP-1 complex subunit mu-1

3

20

Small-scale

0.827

High

225797

AP2B1
AP-2 complex subunit beta

2

15

High-throughput

0.789

High

225865

GGA1
ADP-ribosylation factor-binding protein GGA1

2

10

Small-scale

0.768

High

225837

NECP1
Adaptin ear-binding coat-associated protein 1

2

12

Small-scale

0.754

High

225813

RABE1
Rab GTPase-binding effector protein 1

6

6

Small-scale

0.729

High

225821

AAGAB
Alpha- and gamma-adaptin-binding protein p34

5

3

High-throughput

0.717

High

225866

SYNRG
Synergin gamma

4

4

Small-scale

0.694

High

225849

AP1S3
AP-1 complex subunit sigma-3

1

20

High-throughput

0.691

High

225811

EPN4
Clathrin interactor 1

3

20

Small-scale

0.651

High

225799

ARF1
ADP-ribosylation factor 1

1

20

Small-scale

0.647

High

225810

ARFRP
ADP-ribosylation factor-related protein 1

1

20

Small-scale

0.647

High

225861

GGA3
ADP-ribosylation factor-binding protein GGA3

1

14

Small-scale

0.647

High

225864

GGA2
ADP-ribosylation factor-binding protein GGA2

1

13

Small-scale

0.647

High

225851

UBL7
Ubiquitin-like protein 7

3

0

High-throughput

0.646

High

225783

EPS15
Epidermal growth factor receptor substrate 15

2

20

Small-scale

0.629

High

225755

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

2

16

High-throughput

0.628

High

225788

AP2S1
AP-2 complex subunit sigma

1

20

Small-scale

0.618

High

225795

ARF6
ADP-ribosylation factor 6

1

20

Small-scale

0.618

High

225754

PRKN
E3 ubiquitin-protein ligase parkin

2

15

High-throughput

0.584

High

225759

EGFR
Epidermal growth factor receptor

2

13

High-throughput

0.584

High

225761

ESR1
Estrogen receptor

2

11

High-throughput

0.571

High

225769

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

4

High-throughput

0.571

High

225774

RAB5A
Ras-related protein Rab-5A

2

3

High-throughput

0.571

High

225823

AFTIN
Aftiphilin

1

2

Small-scale

0.561

High

225863

HTR5B
HEAT repeat-containing protein 5B

1

4

Small-scale

0.561

High

225766

CLCA
Clathrin light chain A

1

15

High-throughput

0.536

High

225767

CLCB
Clathrin light chain B

1

13

High-throughput

0.536

High

225773

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

1

High-throughput

0.536

High

225775

COMT
Catechol O-methyltransferase

1

3

High-throughput

0.536

High

225776

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

4

High-throughput

0.536

High

225784

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

225848

SPT33
Spermatogenesis-associated protein 33

1

1

High-throughput

0.536

High

225860

GTSE1
G2 and S phase-expressed protein 1

1

4

High-throughput

0.536

High

225765

SYPH
Synaptophysin

1

0

Small-scale

0.529

High

225779

AKT2
RAC-beta serine/threonine-protein kinase

1

5

High-throughput

0.515

High

225789

ATX1
Ataxin-1

1

5

High-throughput

0.515

High

49144

POTB3
POTE ankyrin domain family member B3

2

5

High-throughput

0.504

High

225787

PSN2
Presenilin-2

1

1

Small-scale

0.501

High

225829

CCD91
Coiled-coil domain-containing protein 91

1

1

Small-scale

0.501

High

225853

KI13A
Kinesin-like protein KIF13A

1

9

Small-scale

0.501

High

225859

PLK2
Serine/threonine-protein kinase PLK2

1

6

Small-scale

0.501

High

225868

SNX9
Sorting nexin-9

1

5

Small-scale

0.501

High

225822

POTEG
POTE ankyrin domain family member G

1

5

High-throughput

0.489

High

225825

PACS1
Phosphofurin acidic cluster sorting protein 1

1

0

Small-scale

0.480

High

159426

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

7

High-throughput

0.479

High

172297

XPO1
Exportin-1

1

15

High-throughput

0.479

High

178111

NPC1
NPC intracellular cholesterol transporter 1

1

2

High-throughput

0.479

High

217559

TGON2
Trans-Golgi network integral membrane protein 2

1

12

High-throughput

0.479

High

220456

RNF13
E3 ubiquitin-protein ligase RNF13

1

8

Small-scale

0.479

High

225753

SPOP
Speckle-type POZ protein

1

2

High-throughput

0.479

High

225756

TM1L1
TOM1-like protein 1

1

9

High-throughput

0.479

High

225757

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

225760

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.479

High

225762

NTRK1
High affinity nerve growth factor receptor

1

14

High-throughput

0.479

High

225763

P53
Cellular tumor antigen p53

1

3

High-throughput

0.479

High

225770

HSP7C
Heat shock cognate 71 kDa protein

1

5

High-throughput

0.479

High

225771

IFM1
Interferon-induced transmembrane protein 1

1

8

High-throughput

0.479

High

225778

PML
Protein PML

1

4

High-throughput

0.479

High

225780

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.479

High

225782

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

225785

AMPH
Amphiphysin

1

20

Small-scale

0.479

High

225790

TERA
Transitional endoplasmic reticulum ATPase

1

7

High-throughput

0.479

High

225792

CORO7
Coronin-7

1

1

Small-scale

0.479

High

225793

RL27
Large ribosomal subunit protein eL27

1

1

High-throughput

0.479

High

225796

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

4

High-throughput

0.479

High

225798

MAP1A
Microtubule-associated protein 1A

1

9

Small-scale

0.479

High

225803

TF65
Transcription factor p65

1

1

High-throughput

0.479

High

225804

EP300
Histone acetyltransferase p300

1

13

High-throughput

0.479

High

225807

SMAD4
Mothers against decapentaplegic homolog 4

1

2

High-throughput

0.479

High

225809

CUL4A
Cullin-4A

1

3

High-throughput

0.479

High

225812

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

6

High-throughput

0.479

High

225816

LTOR1
Ragulator complex protein LAMTOR1

1

6

High-throughput

0.479

High

225819

ZN746
Zinc finger protein 746

1

1

High-throughput

0.479

High

225826

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

225827

ATG9A
Autophagy-related protein 9A

1

5

High-throughput

0.479

High

225830

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

Small-scale

0.479

High

225833

RHG24
Rho GTPase-activating protein 24

1

4

High-throughput

0.479

High

225834

RHG18
Rho GTPase-activating protein 18

1

8

High-throughput

0.479

High

225835

RN149
E3 ubiquitin-protein ligase RNF149

1

5

High-throughput

0.479

High

225836

SERB1
SERPINE1 mRNA-binding protein 1

1

4

High-throughput

0.479

High

225839

SMAP2
Stromal membrane-associated protein 2

1

11

High-throughput

0.479

High

225840

ASB10
Ankyrin repeat and SOCS box protein 10

1

4

High-throughput

0.479

High

225842

ESR2
Estrogen receptor beta

1

11

High-throughput

0.479

High

225843

FBXW7
F-box/WD repeat-containing protein 7

1

4

High-throughput

0.479

High

225850

PASK
PAS domain-containing serine/threonine-protein kinase

1

5

High-throughput

0.479

High

225854

SENP3
Sentrin-specific protease 3

1

1

Small-scale

0.479

High

225855

PKHA4
Pleckstrin homology domain-containing family A member 4

1

18

High-throughput

0.479

High

225858

CALY
Neuron-specific vesicular protein calcyon

1

1

Small-scale

0.479

High

225862

TLS1
Splicing factor C9orf78

1

4

High-throughput

0.479

High

225841

BAALC
Brain and acute leukemia cytoplasmic protein

1

0

Small-scale

0.460

High

225801

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

225814

FSCN1
Fascin

1

0

High-throughput

0.458

High

225844

FBX32
F-box only protein 32

1

0

Small-scale

0.458

High

225846

GASP2
G-protein coupled receptor-associated sorting protein 2

1

0

High-throughput

0.458

High

225768

TAU
Microtubule-associated protein tau

1

17

High-throughput

0.445

High

225786

CXCR3
C-X-C chemokine receptor type 3

1

3

High-throughput

0.445

High

225802

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

12

High-throughput

0.445

High

225808

VPP3
V-type proton ATPase 116 kDa subunit a 3

1

2

High-throughput

0.445

High

225815

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.445

High

225817

PKHA7
Pleckstrin homology domain-containing family A member 7

1

15

High-throughput

0.445

High

225820

MFS12
Major facilitator superfamily domain-containing protein 12

1

3

High-throughput

0.445

High

225831

MFS6L
Major facilitator superfamily domain-containing protein 6-like

1

4

High-throughput

0.445

High

225832

S15A3
Solute carrier family 15 member 3

1

4

High-throughput

0.445

High

225838

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

2

High-throughput

0.445

High

225857

SL2A8
Solute carrier family 2, facilitated glucose transporter member 8

1

6

High-throughput

0.445

High

225867

SL9A8
Sodium/hydrogen exchanger 8

1

5

High-throughput

0.445

High

225847

Z512B
Zinc finger protein 512B

1

2

High-throughput

0.439

High

104902

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

225758

AGR2
Anterior gradient protein 2 homolog

1

6

High-throughput

0.437

High

225764

JUN
Transcription factor Jun

1

4

Small-scale

0.437

High

225772

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.437

High

225777

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

225781

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

225806

TIF1B
Transcription intermediary factor 1-beta

1

4

High-throughput

0.437

High

225824

LMBRL
Protein LMBR1L

1

2

High-throughput

0.437

High

225828

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.437

High

225818

S18B1
MFS-type transporter SLC18B1

1

4

High-throughput

0.407

High


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Last updated: 11Aug2025